1. Results for HbA1c (A), severe or BG-confirmed symptomatic hypoglycemia (B), change in body weight (C), daily total insulin dose (D), FPG (E), and nine-point SMPG profiles (F).
Results for HbA1c (A), severe or BG-confirmed symptomatic hypoglycemia (B), change in body weight (C), daily total insulin dose (D), FPG (E), and nine-point SMPG profiles (F). A: Mean observed values with error bars (SEM) based on FAS. B: Mean cumulative frequency based on the SAS. Severe or BG-confirmed symptomatic describes an episode that is severe according to the ADA classification or BG-confirmed by a plasma glucose value <3.1 mmol/L (<56 mg/dL) with symptoms consistent with hypoglycemia. C: Least square mean (LSMean) values with error bars (SE of estimated LSMean) based on FAS, using MMRM. D: Mean observed values with error bars (SEM) based on the SAS. E: Mean observed values with error bars (SEM) based on FAS. F: Mean observed values with error bars (SEM) based on FAS. *Statistically significant difference between EOT means in favor of IGlar U100 + IAsp vs. IDegLira.
Liana K. Billings et al. Dia Care 2018;41:
©2018 by American Diabetes Association