1. My Treatment Approach to Hairy Cell Leukemia
Rahul R. Naik, MD, Alan Saven, MD 
Mayo Clinic Proceedings 
Volume 87, Issue 1, Pages (January 2012)
DOI: /j.mayocp
Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions

2. FIGURE 1
Peripheral blood smear specimen showing circumferential cytoplasmic projections characteristic of hairy cell leukemia (Wright-Giemsa, original magnification ×1000).
Photomicrograph courtesy of Robert W. Sharpe, MD, Department of Pathology, Scripps Clinic, La Jolla, CA.
Mayo Clinic Proceedings  , 67-76DOI: ( /j.mayocp )
Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions

3. FIGURE 2
Bone marrow biopsy specimen from patient with hairy cell leukemia showing hypercellularity with hairy cells having nuclei widely separated by abundant cytoplasm, giving characteristic “fried egg” appearance (hematoxylin-eosin, original magnification ×600).
Photomicrograph courtesy of Robert W. Sharpe, MD, Department of Pathology, Scripps Clinic, La Jolla, CA.
Mayo Clinic Proceedings  , 67-76DOI: ( /j.mayocp )
Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions

4. FIGURE 3
Treatment algorithm. aCladribine preferred because of its ease of administration, favorable toxicity profile, and higher complete response rates. bIndicates consider switching to other purine analog given lack of cross-resistance. HCL = hairy cell leukemia.
Mayo Clinic Proceedings  , 67-76DOI: ( /j.mayocp )
Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions