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Severe Spruelike Enteropathy Associated With Olmesartan

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Presentation on theme: "Severe Spruelike Enteropathy Associated With Olmesartan"— Presentation transcript:

1 Severe Spruelike Enteropathy Associated With Olmesartan
Alberto Rubio-Tapia, MD, Margot L. Herman, MD, Jonas F. Ludvigsson, MD, PhD, Darlene G. Kelly, MD, PhD, Thomas F. Mangan, MD, Tsung-Teh Wu, MD, PhD, Joseph A. Murray, MD  Mayo Clinic Proceedings  Volume 87, Issue 8, Pages (August 2012) DOI: /j.mayocp Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions

2 FIGURE Photomicrographs showing reversible spruelike enteropathy associated with olmesartan (hematoxylin-eosin, original magnification ×100). A, Duodenal biopsy specimen obtained while the patient was taking olmesartan shows total villous atrophy and intraepithelial lymphocytosis. B, Biopsy specimen obtained 6 months after withdrawal of olmesartan and initiation of a gluten-containing diet shows recovery of villi on duodenal mucosa. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2012 Mayo Foundation for Medical Education and Research Terms and Conditions


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