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A 38-year-old woman presented with personality and behavioral changes associated with progressive drug-resistant epilepsy. A 38-year-old woman presented.

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Presentation on theme: "A 38-year-old woman presented with personality and behavioral changes associated with progressive drug-resistant epilepsy. A 38-year-old woman presented."— Presentation transcript:

1 A 38-year-old woman presented with personality and behavioral changes associated with progressive drug-resistant epilepsy. A 38-year-old woman presented with personality and behavioral changes associated with progressive drug-resistant epilepsy. Memory testing revealed an anterograde episodic memory disorder, and electroencephalography showed TL epileptiform discharges. A, A selective hyperintensity in the hippocampi that extended to the amygdalae bilaterally was noticed on an axial FLAIR image, predominantly on the left side (arrow). B, Imaging follow-up revealed bilateral hippocampal sclerosis, which is shown in a coronal FLAIR image (arrowheads). Whole-body PET/CT and pelvic sonography were unremarkable (not shown). Autoimmune encephalitis was suggested, and a high titer of GAD65 antibodies was confirmed. A.J. da Rocha et al. AJNR Am J Neuroradiol 2015;36: ©2015 by American Society of Neuroradiology

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