1. A healthy 46-year-old woman presented with an acute onset of psychiatric disturbance and hyponatremia.
A healthy 46-year-old woman presented with an acute onset of psychiatric disturbance and hyponatremia. A, Bilateral hyperintensity and mild enlargement were noticed on an axial FLAIR image in both hippocampi and amygdalae. B, No abnormal restricted diffusion was observed on DWI. The final diagnosis was anti-VGKC encephalitis. Restricted diffusion may occur in approximately 50% of patients at this phase and is usually restricted to the limbic system. The presence of faciobrachial dystonic or tonic seizures, hyponatremia, and unremarkable CSF in the setting of LE should raise concern that anti-LGI1 encephalitis is present.
A.J. da Rocha et al. AJNR Am J Neuroradiol 2015;36:
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