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Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease  Nan Zhang, MD, PhD, Thibaut Van Zele, MD, PhD, Claudina.

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Presentation on theme: "Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease  Nan Zhang, MD, PhD, Thibaut Van Zele, MD, PhD, Claudina."— Presentation transcript:

1 Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease 
Nan Zhang, MD, PhD, Thibaut Van Zele, MD, PhD, Claudina Perez-Novo, PhD, Nicholas Van Bruaene, MD, Gabriele Holtappels, Natalie DeRuyck, Paul Van Cauwenberge, MD, PhD, Claus Bachert, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 122, Issue 5, Pages (November 2008) DOI: /j.jaci Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Semiquantitative evaluation of granulocyte tissue infiltration. Values are reported as medians and interquartile ranges for each group. The significance level was set at an α value of .05. Concentrations for ECP and MPO are reported as medians and interquartile ranges for each group, and the significance level equals a P value of .05. From these data, an ECP/MPO ratio was calculated. HE, Hematoxylin. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 mRNA levels for T-bet, GATA-3, RORC, and Foxp3 transcription factors normalized to the levels of β-actin, hydroxymethylbilane synthase, and elongation factor 1 as housekeeping genes in each group. Values are reported as medians and interquartile ranges for each group. The significance level was set at a P value of .05. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig 3 Concentrations of soluble IL-2 receptor α (sIL-2Rα), IL-5, IFN-γ, IL-1β, IL-6, IL-17A, eotaxin, IgE, and TGF-β1 protein in each group. Values are reported as medians and interquartile ranges for each group. The significance level was set at a P value of .05. Please note that the TGF-β1 protein data refer to patients without asthma (see the Results section). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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