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A Novel Role for the Fibroblast Growth Factor 21 in Acute Pancreatitis

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Presentation on theme: "A Novel Role for the Fibroblast Growth Factor 21 in Acute Pancreatitis"— Presentation transcript:

1 A Novel Role for the Fibroblast Growth Factor 21 in Acute Pancreatitis
Hana Algül  Gastroenterology  Volume 137, Issue 5, Pages (November 2009) DOI: /j.gastro Copyright © Terms and Conditions

2 Figure 1 Schematic illustration of the effects of FGF21 during AP. Acinar cell damage results in FGF21 expression. Then, PDGF and subsequent activation of PSCs are inhibited. Furthermore, FGF21 can act as inhibitor of the Egr-1 pathway by acting in a paracrine/autocrine fashion via the βKlotho receptor. Gastroenterology  , DOI: ( /j.gastro ) Copyright © Terms and Conditions


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