1. Advanced Biology
Connective Tissue

2. Found everywhere in body

3. Connective Tissue Proper
Cartilage
Bone
Blood

4. Binding and Support
Protection
Insulation
Transportation

5. Embryonic Tissue where all other types arise from

6. Cartilage – avascular
Dense – poor vascularization
All others have rich supply

7. Non-living
Allows for weight bearing, great tension, endures abrasion

8. GROUND Amorphous – unstructured Interstitial fluid
Cell adhesion proteins – fibronectin and laminin =glue

9. GROUND
Holds fluid
Acts as a sieve, or medium through which nutrients diffuse

10. FIBERS
Provide support

11. COLLAGEN Made of protein collagen
Very tough, ability to resist longitudinal stress
Appear white – white fibers

12. ELASTIC Made of protein elastin Stretch and recoil (rubber band)
Skin, lungs
Appear yellow – yellow fibers

13. RETICULAR Fine collagenous
Branch extensively, form networks surrounded by BV
Found where CT meets other tissues

15. CELLS
-blast = immature
-cyte= mature

16. FIBROBLAST
Immature connective tissue proper

17. CHONDROBLAST
Immature cartilage

18. OSTEOBLAST
Immature bone cell

19. HEMOCYTOBLAST
Immature blood cell

20. WHITE BLOOD CELLS
Neutrophils
Eosinophils
Lymphocytes

21. PLASMA CELLS
Produce Antibodies

22. MAST CELLS Clustered in tissue spaces
Detect foreign substances, initate inflammatory response
Heparin – anticoagulant (free in blood stream)
Histamine – makes capillaries leaky

23. MACROPHAGES Large, irregular shaped – phagocytize foreign material
All have certain roles: Histiocytes -
Kupffer cells – liver
Microglial – brain

24. EMBRYONIC 1st Definitive Layer
Layer from which all others differentiate
Temporary – Wharton’s Jelly which supports umbilical cord

25. CONNECTIVE TISSUE PROPER
Loose
Dense

26. Loose = Areolar, Adipose, Reticular
Dense = Dense regular, Dense irregular, elastic