Presentation is loading. Please wait.

Presentation is loading. Please wait.

Figure 1. Yvis platform overview

Similar presentations


Presentation on theme: "Figure 1. Yvis platform overview"— Presentation transcript:

1 Figure 1. Yvis platform overview
Figure 1. Yvis platform overview. (A) The data input box presents two possibilities to input sequences to be analysed ... Figure 1. Yvis platform overview. (A) The data input box presents two possibilities to input sequences to be analysed in Yvis (user input files and selection from the Yvis database). It presents filter options for sequences from the Yvis database (redundancy and engineered chains) and actions taken by the platform to process the user input files. (B) The analysis box presents the options to visualize a multiple sequence alignment of antibody variable domains and the filter possibilities. The user can generate a new subset of sequences to be analysed, by selecting specific filters. The analysis can be displayed by the Collier de Diamants on one or two layers (I). Additionally, the user can compare the multiple sequence alignment with a reference sequence (II), and visualize data on putative contacts with the antigen (III). Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of Nucleic Acids Research.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact Nucleic Acids Res, gkz387, The content of this slide may be subject to copyright: please see the slide notes for details.

2 Figure 2. Collier de Diamants representation of antibody sequences obtained from HIV-infected patients. (A) ... Figure 2. Collier de Diamants representation of antibody sequences obtained from HIV-infected patients. (A) Visualization of the alignment of 97 751 heavy chain sequences derived from the IGHV1-2*02 allele. Positions between and and positions between and were omitted. The box presents part of the detailed bar chart for position 36 showing the residue frequency in this position. (B) Visualization of the alignment of 21 heavy chain sequences of HIV neutralizing antibodies. In both visualizations, the IGHV1-2*02 germline sequence was used as comparison sequence. As this sequence includes only the V gene portion of the variable domain, gaps were inserted in the comparison sequence. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of Nucleic Acids Research.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact Nucleic Acids Res, gkz387, The content of this slide may be subject to copyright: please see the slide notes for details.


Download ppt "Figure 1. Yvis platform overview"

Similar presentations


Ads by Google