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Report of Eight Recent Cases of Locally Advanced Primary Pulmonary Artery Sarcomas: Failure of Doxorubicin-Based Chemotherapy  Nicolas Penel, MD, PhD,

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Presentation on theme: "Report of Eight Recent Cases of Locally Advanced Primary Pulmonary Artery Sarcomas: Failure of Doxorubicin-Based Chemotherapy  Nicolas Penel, MD, PhD,"— Presentation transcript:

1 Report of Eight Recent Cases of Locally Advanced Primary Pulmonary Artery Sarcomas: Failure of Doxorubicin-Based Chemotherapy  Nicolas Penel, MD, PhD, Sophie Taieb, MD, Luc Ceugnart, MD, Eric Dansin, MD, Dominique Hoguet, MD, Luc Vanseymortier, MD, Eric Lartigau, MD, PhD  Journal of Thoracic Oncology  Volume 3, Issue 8, Pages (August 2008) DOI: /JTO.0b013e d Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Woman, 52-year old (case 5). Helical CT with contrast: unilateral of massive perfusion defect in right pulmonary artery seems pulmonary embolism. Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e d) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 A, MRI performed 4 weeks later because of failure of anticoagulation. T1-weighted images show intermediate heterogeneous signal intensity in right pulmonary artery with irregular margins and superior vena cava infiltration (arrow). Right pleural effusion appears (arrow head). B, After contrast administration: the lesion seems heterogeneous with large central necrosis. Signal of peripheral zone is enhanced by contrast. Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e d) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

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