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Surgical myectomy versus alcohol septal ablation for obstructive hypertrophic cardiomyopathy: A propensity score–matched cohort  Anita Nguyen, MBBS, Hartzell.

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Presentation on theme: "Surgical myectomy versus alcohol septal ablation for obstructive hypertrophic cardiomyopathy: A propensity score–matched cohort  Anita Nguyen, MBBS, Hartzell."— Presentation transcript:

1 Surgical myectomy versus alcohol septal ablation for obstructive hypertrophic cardiomyopathy: A propensity score–matched cohort  Anita Nguyen, MBBS, Hartzell V. Schaff, MD, Dustin Hang, MD, Rick A. Nishimura, MD, Jeffrey B. Geske, MD, Joseph A. Dearani, MD, Brian D. Lahr, MS, Steve R. Ommen, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 157, Issue 1, Pages e3 (January 2019) DOI: /j.jtcvs Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Flow diagram of the study population.
The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Distribution of PS in the original sample and the PS-matched subset. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Predicted follow-up LVOT resting gradient in myectomy and ASA cases, based on preprocedure gradients. A, Predicted postprocedural gradients using catheter/pressure measurements. B and C, Predicted early (<30 days after procedure) and late transthoracic echocardiography gradients (>30 days to 2 years after septal reduction therapy). LVOT, Left ventricular outflow tract; TTE, transthoracic echocardiography. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Survival in original sample and PS-matched groups. A, Unadjusted survival in the original sample for myectomy and ASA groups. B, Survival of the PS-matched myectomy and ASA groups. The dashed line depicts expected survival in an age-, sex-, and race-matched population. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

6 Figure 5 Freedom from reintervention in myectomy and ASA groups.
The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

7 Figure E1 PS between the 2 groups; back-to-back histograms of the PS distributions before and after matching shown on probability and logit scale. ASA, Alcohol septal ablation. The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

8 Survival in the PS-matched groups.
The Journal of Thoracic and Cardiovascular Surgery  , e3DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions


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