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Reduced-Intensity Allogeneic Transplant in Patients Older Than 55 Years: Unrelated Umbilical Cord Blood Is Safe and Effective for Patients without a Matched.

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Presentation on theme: "Reduced-Intensity Allogeneic Transplant in Patients Older Than 55 Years: Unrelated Umbilical Cord Blood Is Safe and Effective for Patients without a Matched."— Presentation transcript:

1 Reduced-Intensity Allogeneic Transplant in Patients Older Than 55 Years: Unrelated Umbilical Cord Blood Is Safe and Effective for Patients without a Matched Related Donor  Navneet S. Majhail, Claudio G. Brunstein, Marcie Tomblyn, Avis J. Thomas, Jeffrey S. Miller, Mukta Arora, Dan S. Kaufman, Linda J. Burns, Arne Slungaard, Philip B. McGlave, John E. Wagner, Daniel J. Weisdorf  Biology of Blood and Marrow Transplantation  Volume 14, Issue 3, Pages (March 2008) DOI: /j.bbmt Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Probability of (A) PFS and (B) OS. The probability of PFS and OS at 3 years between the 2 graft sources was comparable. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Cumulative incidence of (A) sustained donor engraftment, (B) acute grade II-IV GVHD, and (C) cGVHD. The cumulative incidence of aGVHD was comparable between the 2 graft sources, whereas that for donor engraftment and cGVHD was lower in UCB recipients. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

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