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ATG Prevents Severe Acute Graft-versus-Host Disease in Mismatched Unrelated Donor Hematopoietic Cell Transplantation  Joseph Pidala, Marcie Tomblyn, Taiga.

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Presentation on theme: "ATG Prevents Severe Acute Graft-versus-Host Disease in Mismatched Unrelated Donor Hematopoietic Cell Transplantation  Joseph Pidala, Marcie Tomblyn, Taiga."— Presentation transcript:

1 ATG Prevents Severe Acute Graft-versus-Host Disease in Mismatched Unrelated Donor Hematopoietic Cell Transplantation  Joseph Pidala, Marcie Tomblyn, Taiga Nishihori, Ernesto Ayala, Teresa Field, Hugo Fernandez, Lia Perez, Fred Locke, Melissa Alsina, Jose Leonel Ochoa, Janelle Perkins, Cheryl Tate, Jamie Shapiro, Michelle Conwell, Ryan Bookout, Claudio Anasetti  Biology of Blood and Marrow Transplantation  Volume 17, Issue 8, Pages (August 2011) DOI: /j.bbmt Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Cumulative incidence of grade III-IV aGVHD from date of HCT.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Cumulative incidence of moderate to severe cGVHD (per NIH severity criteria) from date of HCT. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Kaplan-Meier plot of OS from date of HCT. Numbers with available data: 3 months lymph (n = 24), CD4 (n = 11); 6 months lymph (n = 23), CD4 (n = 12); 12 months lymph (n = 13), CD4 (n = 8). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Absolute lymphocyte and CD4 lymphocyte reconstitution at 3, 6, and 12 months following date of HCT. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

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