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Characteristics of isolated perfused juxtaglomerular apparatus

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Presentation on theme: "Characteristics of isolated perfused juxtaglomerular apparatus"— Presentation transcript:

1 Characteristics of isolated perfused juxtaglomerular apparatus
Sadayoshi Ito  Kidney International  Volume 54, Pages S46-S48 (September 1998) DOI: /j x Copyright © 1998 International Society of Nephrology Terms and Conditions

2 Figure 1 Schematic representation of the pipette arrangement used for perfusion of an afferent arteriole (Af-Art) and attached macula densa (MD). Abbreviations are: TALH, thick ascending limb of Henle's loop; GL, glomerulus; DCT, distal convoluted tubule; Ef-Art, efferent arteriole; Hold-Pip, holding pipette; Perf-Pip, perfusion pipette; Exch-Pip, exchange pipette; Pre-Pip, pressure pipette. Kidney International  , S46-S48DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions

3 Figure 2 Left: simultaneous perfusion of an afferent arteriole (Af-Art) and attached macula densa (MD). Right: after perfusion has been established, both the MD and Af-Art can be visualized. Abbreviations are: DCT, distal convoluted tubule; TAL, thick ascending limb of the loop of Henle. Kidney International  , S46-S48DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions

4 Figure 3 Constriction of the afferent arteriole induced by a high [NaCl] at the macula densa (MD). With the afferent arteriole in focus, the MD cannot be seen clearly. Kidney International  , S46-S48DOI: ( /j x) Copyright © 1998 International Society of Nephrology Terms and Conditions


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