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Volume 78, Issue 2, Pages (July 2010)

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Presentation on theme: "Volume 78, Issue 2, Pages (July 2010)"— Presentation transcript:

1 Volume 78, Issue 2, Pages 127-129 (July 2010)
The nanopeptide hormone vasopressin is a new player in the modulation of renal Na+– Cl− cotransporter activity  Gerardo Gamba  Kidney International  Volume 78, Issue 2, Pages (July 2010) DOI: /ki Copyright © 2010 International Society of Nephrology Terms and Conditions

2 Figure 1 Known vasopressin actions in the nephron. Vasopressin is well known for its activation properties in renal tubules via its interaction with the V2-type receptor, particularly in the thick ascending limb of Henle (TAL) and collecting duct (CD). Pedersen et al.8 show that vasopressin is also an activator of the Na+–Cl− cotransporter (NCC) in the distal convoluted tubule (DCT). (a) The DCT in the absence of vasopressin. (b) The DCT in the presence of vasopressin. Kidney International  , DOI: ( /ki ) Copyright © 2010 International Society of Nephrology Terms and Conditions


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