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Schizophrenia Clinical description Biological explanations

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Presentation on theme: "Schizophrenia Clinical description Biological explanations"— Presentation transcript:

1 Schizophrenia Clinical description Biological explanations
Clinical description Biological explanations Psychological explanations

2 Schizophrenia Schizophrenia is not a multiple personality
Schizophrenia is not a multiple personality A psychotic disorder involving a break with reality Many different manifestations with a few shared features

3 Schizophrenia diagnosis
At least two of the following: Hallucinations (us. auditory or somatic) Delusions (oft. linked to hallucinations) Disorganised speech Disorganised or catatonic behaviour Negative symptoms Social & occupational dysfunction Duration of several months

4 Schizophrenia diagnosis
Diagnostic subtypes Paranoid Catatonic Disorganised Undifferentiated Type 1 - Episodic, mainly positive symptoms Type 2 - Chronic, mainly negative symptoms

5 Schizophrenia prevalence
1% lifetime risk in general population Holds true for most geographical areas although rates do vary Abnormally high in Southern Ireland, Croatia; significantly lower rates in Italy, Spain (Torrey, 2002) Risk factors include low SES, minority ethnicity, urban residence

6 Schizophrenia onset Source: CIHI (2001)

7 Schizophrenia prognosis
‘Rule of the thirds’ (rule of thumb): 1/3 recover more or less completely 1/3 episodic impairment 1/3 chronic decline Confirmed in US & UK (Stevens, 1978) With treatment about 60% of patients manage a relatively normal life Prognosis better in non-industrialised societies

8 Schizophrenia explanations
Biological Genetics Neurochemicals & hormones Structural brain abnormalities Psychological Family dynamics Life stress Urbanicity


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