1. Epigenetic modifications as new targets for liver disease therapies
Müjdat Zeybel, Derek A. Mann, Jelena Mann 
Journal of Hepatology 
Volume 59, Issue 6, Pages (December 2013)
DOI: /j.jhep
Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

2. Fig. 1
Epigenetic mechanisms that regulate gene expression. The mammalian genome is packaged in the nucleus via wrapping of DNA around histones, forming a structure known as chromatin. The on and off state of gene expression is regulated by DNA methylation, post-translational modifications of various residues within histone tails, and non-coding RNAs.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

3. Fig. 2
Enzymes that control histone lysine methylation and acetylation are targets for numerous drugs that are being developed or already used clinically. HDAC, histone deacetylase; HAT, histone acetyltransferase; KMT, histone lysine methyltransferas; KDM, histone lysine demethylase.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2013 European Association for the Study of the Liver Terms and Conditions

4. Journal of Hepatology 2013 59, 1349-1353DOI: (10. 1016/j. jhep. 2013
Copyright © 2013 European Association for the Study of the Liver Terms and Conditions