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Membranes and Transport

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1 Membranes and Transport
Chapters 7.3

2 Plasma Membrane Fluid Mosaic Model Phospholipids Bilayers
Membrane Proteins Cholesterol

3 Transport across Membranes
Gradient Passive Transport diffusion osmosis facilitated diffusion Active Transport Cell Surfaces

4 Fluid Mosaic Model describes both the structure and function of biological membranes states that the membrane is a “fluid” (not static) structure, membrane molecules “float” or “slide” past one another also is a “mosaic” - art term describing a large picture made of many small parts

5 1st Major Part: Phospholipids
are amphipathic Contain two regions: head phosphate polar, hydrophilic, interacts with water tails (2) fatty acids (saturated or unsaturated) nonpolar, hydrophobic, repelled by water

6 Major Part 2-Membrane Proteins
are either inserted through the membrane = integral proteins transport proteins - channels and carriers enzymes receptor proteins or are associated w/ the membrane surface = peripheral proteins act as sites for attachment to the cytoskeleton or extracellular matrix

7 Major Part 3 - Cholesterol:
is the basis of all steroid molecules acts to stabilize the structure of membranes affects the “fluidity” of the membrane

8 Bilayers: are arranged from two layers of phospholipids; arranged tail-to-tail are the basic structure for all membranes have a hydrophobic region (lipid tails) that acts as a selectively permeable barrier give membranes a condition known as selective permeability

9 SELECTIVE PERMEABILITY
Some things can cross the membrane; other things cannot... This means the membrane is important for HOMEOSTASIS-keeps the internal part of the cell stable. The Membrane is the Cell’s BOUNCER

10 Cross Easily small molecules nonpolar molecules water oxygen
carbon dioxide nonpolar molecules lipids steroids

11 Doesn’t Cross Easily Large molecules Polar and ionic compounds
DNA, Proteins, etc. Polar and ionic compounds sugar salts

12 Gradient definition: difference in concentrations, ions, etc. over a distance helps describe how substances move from one place to another Due to the random movement of molecules leads to movement from areas of high concentration to areas of low concentration

13 Passive Transport any movement of molecules “down” gradient
does not require energy diffusion: movement of a substance from high concentrations to low concentrations osmosis: diffusion of water across a selectively permeable membrane facilitated diffusion: diffusion of a molecule across a membrane through a membrane protein

14 Osmosis: diffusion of water across a selectively permeable membrane
hypertonic: solution with a higher concentration of solutes than its surroundings hypotonic: solution with a lower concentration of solutes than its surroundings isotonic: solution with concentrations equal to the surroundings

15 Active Transport movement of molecules against or “up” their concentration gradient REQUIRES ENERGY = ATP compare:both are types of transport contrast: active requires energy; moves substances up the gradient and from low to high concentration passive doesn’t require energy; moves down the gradient and from high to low concentration

16 Explain the movement… of water across a selectively permeable membrane in terms of hyper-, iso-, and hypotonic solutions water moves “down” its concentration gradient water’s concentration gradient is opposite that of its solutes, SO water moves from regions of low solute concentration to regions of high solute concentration water moves from hypotonic to hypertonic

17 Water Balance w/out walls
hypertonic-lose water and shrivel (crenation) hypotonic-gain water, swell, and possibly burst (lyse) must live in isotonic environments or have adaptations for osmoregulation

18 Water Balance - cont’d. with walls
hypotonic-water moves into the cell and presses against the wall, causing a turgid cell isotonic solutions-flaccid cells hypertonic-plasmolysis - membrane pulls away from the cell wall as it shrivels

19 Exocytosis movement of large molecules out of the cell
requires vesicles for transport

20 Endocyotsis movement of large molecules into the cell
phagocytosis: cell eating-one cell engulfs another pinocytosis: cell drinking-cells bring in fluid from the surroundings

21 Transport Terms to Know
Diffusion Osmosis Facilitated Diffusion Active transport Exocytosis Endocytosis


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