Presentation is loading. Please wait.

Presentation is loading. Please wait.

Supplemental Figure 1 A GENE chr location (hg18) SNP sample ID TLR2

Published byGilles Lépine Modified over 5 years ago

Similar presentations

Presentation on theme: "Supplemental Figure 1 A GENE chr location (hg18) SNP sample ID TLR2"— Presentation transcript:

1 Supplemental Figure 1 A GENE chr location (hg18) SNP sample ID TLR2 chr4 CCC-CTC WBM40 AGC-CGC WBM51 TTT-TCT WBM57 TLR4 chr9 TGC-TAC WBM69 B C D #55 E no agonist PAM2CSK4 GFP WT F217S GFP WT F217S p-p38 b-actin Figure S1. Mutational analysis of TLRs in MDS. (a) Identification of three rare SNPs of TLR1 and one rare SNP of TLR4 by captured deep sequencing in MDS BM-MNCs. (b) The presence of TLR2-F217S in both BM-MNC and BM-CD3+ cells of one case of MDS. (c) Lack of TLR2-F217S in BM-MNC or BM-CD3+ cells of another case of MDS. (d) Luciferase analysis of activation of AP1 by WT and F217S TLR2 in transfected 293T cells. Cells were exposed to either no agonist or to PAM2CSK4. (e) Western blot characterization of p38 phosphorylation in 293T cells transfected with either WT or F217S TLR2 and treated with no agonist, MALP2 or PAM2CSK4. Top, Western blot analysis of p-p38; Bottom, Quantification of p-p38 band densities.

Download ppt "Supplemental Figure 1 A GENE chr location (hg18) SNP sample ID TLR2"

Similar presentations

ATG GAG GAA GAA GAT GAA GAG ATC TTA TCG TCT TCC GAT TGC GAC GAT TCC AGC GAT AGT TAC AAG GAT GAT TCT CAA GAT TCT GAA GGA GAA AAC GAT AAC CCT GAG TGC GAA.

ATG GAG GAA GAA GAT GAA GAG ATC TTA TCG TCT TCC GAT TGC GAC GAT TCC AGC GAT AGT TAC AAG GAT GAT TCT CAA GAT TCT GAA GGA GAA AAC GAT AAC CCT GAG TGC GAA.
Supplementary Fig.1: oligonucleotide primer sequences.

Supplementary Fig.1: oligonucleotide primer sequences.
Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway Supplementary Data Files in this Data Supplement: Supplementary.

Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway Supplementary Data Files in this Data Supplement: Supplementary.
Supplementary data d a c d ab b Figure S1. Quantification of the Western blot data in figure 4C. The area density of each band was measured with a UVP.

Supplementary data d a c d ab b Figure S1. Quantification of the Western blot data in figure 4C. The area density of each band was measured with a UVP.
Sh-luc shSCP1-1 * IB: c-Myc IB: Tubulin shSCP1-2 IB: p-Ser62 1.0 1.8 2.5 60KD 70KD 60KD 70KD 1 2 3 (abnova) sh-luc shSCP1-1 * IB: c-Myc IB: Tubulin shSCP1-2.

Sh-luc shSCP1-1 * IB: c-Myc IB: Tubulin shSCP1-2 IB: p-Ser KD 70KD 60KD 70KD (abnova) sh-luc shSCP1-1 * IB: c-Myc IB: Tubulin shSCP1-2.
TRS1 rpS6 28S 18S B A Oligo(dT) Input +MN TRS1 +m 7 GTP + -- + +- -- - + + - His PABP Figure S1. pTRS1 associates with the mRNA body independent of the.

TRS1 rpS6 28S 18S B A Oligo(dT) Input +MN TRS1 +m 7 GTP His PABP Figure S1. pTRS1 associates with the mRNA body independent of the.
B Supplementary Fig S1. (A) ZR75- and MCF7-PELP1 knockdown cells were generated as described in methods section. Pooled colonies were analyzed for PELP1.

B Supplementary Fig S1. (A) ZR75- and MCF7-PELP1 knockdown cells were generated as described in methods section. Pooled colonies were analyzed for PELP1.
Leimgruber et al. Supplementary Figure 1 Supplementary Figure 1. The S’-Y’ and S-Y modules of the HLA-DRA gene exhibit lower levels of H4Ac, reduced nucleosome.

Leimgruber et al. Supplementary Figure 1 Supplementary Figure 1. The S’-Y’ and S-Y modules of the HLA-DRA gene exhibit lower levels of H4Ac, reduced nucleosome.
AntimiR-30b Inhibits TNF-α Mediated Apoptosis and Attenuated Cartilage Degradation through Enhancing Autophagy Cell Physiol Biochem 2016;40:883-894 -

AntimiR-30b Inhibits TNF-α Mediated Apoptosis and Attenuated Cartilage Degradation through Enhancing Autophagy Cell Physiol Biochem 2016;40:
Finding the potential miRNA-binding sites of the selected SNPs

Finding the potential miRNA-binding sites of the selected SNPs
Figure 1. Enhancement of ERα activity by Constitutively Active MEKK1 in Endometrial Cancer Cells A, Ishikawa cells were transfected with 0.5 μg EREe1bCAT.

Figure 1. Enhancement of ERα activity by Constitutively Active MEKK1 in Endometrial Cancer Cells A, Ishikawa cells were transfected with 0.5 μg EREe1bCAT.
Volume 141, Issue 4, Pages e5 (October 2011)

Volume 141, Issue 4, Pages e5 (October 2011)
Caspase‐2 activation is a prerequisite for TRAIL‐mediated apoptosis.

Caspase‐2 activation is a prerequisite for TRAIL‐mediated apoptosis.
Phosphorylation of serine 73 targets SREBP-1c for ubiquitination and proteasomal degradation Phosphorylation of serine 73 targets SREBP-1c for ubiquitination.

Phosphorylation of serine 73 targets SREBP-1c for ubiquitination and proteasomal degradation Phosphorylation of serine 73 targets SREBP-1c for ubiquitination.
Takehiko Dohi, Fang Xia, Dario C. Altieri  Molecular Cell 

Takehiko Dohi, Fang Xia, Dario C. Altieri  Molecular Cell 
Calcium regulates ERK nuclear association, but not its activation.

Calcium regulates ERK nuclear association, but not its activation.
The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCθ and ERK pathways by Gilles Despouy, Marjorie Joiner, Emilie Le Toriellec,

The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCθ and ERK pathways by Gilles Despouy, Marjorie Joiner, Emilie Le Toriellec,
Volume 126, Issue 1, Pages (January 2004)

Volume 126, Issue 1, Pages (January 2004)
Volume 81, Issue 1, Pages (January 2012)

Volume 81, Issue 1, Pages (January 2012)
FAM49B controls T cell activation by regulating cytoskeleton remodeling. FAM49B controls T cell activation by regulating cytoskeleton remodeling. (A) J.FAM49B.

FAM49B controls T cell activation by regulating cytoskeleton remodeling. FAM49B controls T cell activation by regulating cytoskeleton remodeling. (A) J.FAM49B.

Similar presentations

Ads by Google