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Advantages of an early invasive approach in acute coronary syndromes

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Presentation on theme: "Advantages of an early invasive approach in acute coronary syndromes"— Presentation transcript:

1 Advantages of an early invasive approach in acute coronary syndromes
Steven J. Kernis, MD, Barry A. Franklin, PhD, Keisha R. Sandberg, MPH, William W. O'Neill, MD, Peter A. McCullough, MD, MPH  The American Journal of Medicine  Volume 115, Issue 8, Pages (December 2003) DOI: /j.amjmed

2 Figure Overview of the results of clinical trials of early invasive versus conservative therapy in patients with unstable angina (UA) or myocardial infarction (MI) without ST-segment elevation. FRISC = Fragmin and Fast Revascularization during Instability in Coronary Artery Disease; ISAR-COOL = Intracoronary Stenting with Antithrombotic Regimen Cooling Off; MATE = Medicine versus Angiography in Thrombolytic Therapy; RITA = Randomized Intervention Trial in Unstable Angina; TACTICS-TIMI = Treat angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy–Thrombolysis in Myocardial Infarction; TIMI = Thrombolysis in Myocardial Infarction; TRUCS = Treatment of Refractory Unstable angina in geographically isolated areas without Cardiac Surgery: invasive versus conservative strategy; VANQWISH = Veterans Affairs Non-Q-Wave Infarction Strategies in Hospital; VINO = Value of First Day Angiography/Angioplasty in Evolving Non-ST-Segment Elevation Myocardial Infarction: A Multicenter Randomized Trial. Adapted with permission from Cannon CP, Turpie AG. Unstable angina and non-ST-elevation myocardial infarction: initial antithrombotic therapy and early invasive strategy. Circulation. 2003;107:2640–2645. The American Journal of Medicine  , DOI: ( /j.amjmed )


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