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Linda F. Fried, Trevor J. Orchard, Bertram L. Kasiske 

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Presentation on theme: "Linda F. Fried, Trevor J. Orchard, Bertram L. Kasiske "— Presentation transcript:

1 Effect of lipid reduction on the progression of renal disease: A meta-analysis 
Linda F. Fried, Trevor J. Orchard, Bertram L. Kasiske  Kidney International  Volume 59, Issue 1, Pages (January 2001) DOI: /j x Copyright © 2001 International Society of Nephrology Terms and Conditions

2 Figure 1 Difference in change in the glomerular filtration rate (GFR) for each individual study (♦) and the combined results using a random effects model (⋄). Horizontal lines indicate 95% confidence intervals. The number in parentheses is the number of patients who completed each study. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

3 Figure 2 Funnel plot for the included studies shows the sample size versus the difference in GFR. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

4 Figure 3 L'Abbé plot of differences in GFR between treatment and control, with the area of the circle corresponding to the number of patients included in each study. Circles above the diagonal line indicate a beneficial effect of lipid-lowering agents on GFR compared with control. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

5 Figure 4 Difference in change in albuminuria or proteinuria [Ln(treatment) - Ln(control)] for each individual study (♦) and the combined result using a random effects model (⋄). Horizontal lines indicate 95% confidence intervals. The number in parentheses equals the sample size. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

6 Figure 5 Funnel plot for the included studies shows the sample size versus difference in proteinuria or albuminuria [Ln(treatment) - Ln(control)]. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions


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