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MET Expression Plays Differing Roles in Non–Small-Cell Lung Cancer Patients with or without EGFR Mutation  Ling Huang, MS, She-Juan An, PhD, Zhi-Hong.

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Presentation on theme: "MET Expression Plays Differing Roles in Non–Small-Cell Lung Cancer Patients with or without EGFR Mutation  Ling Huang, MS, She-Juan An, PhD, Zhi-Hong."— Presentation transcript:

1 MET Expression Plays Differing Roles in Non–Small-Cell Lung Cancer Patients with or without EGFR Mutation  Ling Huang, MS, She-Juan An, PhD, Zhi-Hong Chen, MS, Jian Su, MS, Hong-Hong Yan, MS, Yi-Long Wu, FACS, MD  Journal of Thoracic Oncology  Volume 9, Issue 5, Pages (May 2014) DOI: /JTO Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Immunoreactivity of MET in tyrosine kinase inhibitor–naive non–small-cell lung cancer samples. MET was identified in the membranes and cytoplasm of cancerous cells. A, H-score = 270; B, H-score = 180; C, H-score = 60; D, H-score = 0 (200×). Journal of Thoracic Oncology 2014 9, DOI: ( /JTO ) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Survival time of MET overexpression in non–small-cell lung cancer patients with differing EGFR mutation status, in (A) all patients, (B) patients with wild-type EGFR, and (C) patients with EGFR mutations. EGFR, epidermal growth factor reactor; MET, mesenchymal-epithelial transition; MST, median survival time. Journal of Thoracic Oncology 2014 9, DOI: ( /JTO ) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

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