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Sequential Treatment Initiation with Timothy Grass and Ragweed Sublingual Immunotherapy Tablets Followed by Simultaneous Treatment Is Well Tolerated 

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Presentation on theme: "Sequential Treatment Initiation with Timothy Grass and Ragweed Sublingual Immunotherapy Tablets Followed by Simultaneous Treatment Is Well Tolerated "— Presentation transcript:

1 Sequential Treatment Initiation with Timothy Grass and Ragweed Sublingual Immunotherapy Tablets Followed by Simultaneous Treatment Is Well Tolerated  Jennifer Maloney, MD, Gary Berman, MD, Remi Gagnon, MD, David I. Bernstein, MD, Harold S. Nelson, MD, Jörg Kleine-Tebbe, MD, Amarjot Kaur, PhD, Qing Li, PhD, Hendrik Nolte, MD, PhD  The Journal of Allergy and Clinical Immunology: In Practice  Volume 4, Issue 2, Pages e2 (March 2016) DOI: /j.jaip Copyright © 2015 The Authors Terms and Conditions

2 Figure 1 Trial design. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, e2DOI: ( /j.jaip ) Copyright © 2015 The Authors Terms and Conditions

3 Figure 2 Onset and recurrence of local swelling events by treatment period and intensity. For better data visualization, outliers have been removed from the plot (2 subjects). Seven subjects started period 2 treatment on day 13. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, e2DOI: ( /j.jaip ) Copyright © 2015 The Authors Terms and Conditions

4 Figure 3 Proportion of subjects with at least 1 local AE by treatment period and intensity. Subjects could be counted more than once (ie, if a subject experienced both a moderate and a mild reaction, the subject was counted twice). The denominator used was all treated subjects (n = 102). ∗Both tablets attributed as the cause of the AE, or the investigator was not sure which tablet attributed to the AE. The Journal of Allergy and Clinical Immunology: In Practice 2016 4, e2DOI: ( /j.jaip ) Copyright © 2015 The Authors Terms and Conditions


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