1. Follow up – After 11 Months July 2011
VA: OD/OS 20/20
OD/OS no anterior chamber cells
OD/OS no vitreous cells, dry macula
without therapy

2. Follow up – After 16 Months December 2011
VA: OD/OS 20/25 and 20/40
OD/OS anterior chamber cells (1+)
OD/OS snowballs
OS macular cyst
Diagnosis: mild recurrence

3. Follow Up – December 2011– OCT OS

4. Follow up – After 16 Months December 2011
Therapy:
rimexolone topical 2x/d,
systemic prednisolone 70mg/d
systemic acetazolamide(125mg 2x/d)

5. Follow up – After 17 Months January 2012
VA: OD/OS 20/20
OD/OS no anterior chamber cells
OD/OS dry macula
Therapy: rimexolone topical 2x/d, reduction of systemic prednisolone (12.5mg/d for 2 weeks, then 10mg/d) and acetazolamide (62.5mg/d)

6. Follow Up – After 17 Months January 2012 – OCT OS

7. Follow up – After 21 Months Mai 2012
VA: OD/OS 20/20
OD/OS no anterior chamber cells OD/OS dry macula
Therapy: systemic prednisolone 7.5mg/d, stop of topical rimexolone and systemic acetazolamide

8. Follow up – After 28 Months December 2013
VA: OD/OS 20/20
OD/OS no anterior chamber cells OD/OS dry macula
Therapy: stop of systemic prednisolone 5mg/d

9. Follow up – After 29 Months January 2014
VA: OD/OS 20/20
OD/OS anterior chamber cells (2+), iris nodules
OD/OS dry macula
Recurrence of anterior uveitis
Therapy: topical prednisolone 5x/d

10. Follow up – After 29 Months January 2014

11. Follow up –After 32 Months April 2014
VA: OD/OS 20/20
OD/OS anterior chamber cells (1+), no iris nodules
OD/OS dry macula
Improvement of anterior chamber cell numbers
Therapy: reduction of topical prednisolone

12. Last follow up – After 39 Months November 2014
VA: OD/OS 20/20
OD/OS anterior chamber cells (1-2+)
OD/OS dry macula
mild recurrence
therapy: topical prednisolone 1x/d

13. Final Diagnosis
Tubulointerstitial nephritis and uveitis syndrome (TINU)
Differential diagnosis
sarcoidosis
tuberculosis

14. Conclusion rare disease often misdiagnosed
most often anterior, but occ. intermediate uveitis
typical finding: increased beta-2-microglobuline in urine
good response to corticosteroids
but recurrences are often, may be treated with immunosuppressents