Presentation is loading. Please wait.

Presentation is loading. Please wait.

Vinod H. Thourani, MD, Hanna A

Published byTerje Nilssen Modified over 5 years ago

Similar presentations

Presentation on theme: "Vinod H. Thourani, MD, Hanna A"— Presentation transcript:

1 Outcomes in Nonagenarians Undergoing Transcatheter Aortic Valve Replacement in the PARTNER-I Trial 
Vinod H. Thourani, MD, Hanna A. Jensen, MD, PhD, Vasilis Babaliaros, MD, Susheel K. Kodali, MD, Jeevanantham Rajeswaran, PhD, John Ehrlinger, PhD, Eugene H. Blackstone, MD, Rakesh M. Suri, MD, Creighton W. Don, MD, PhD, Gabriel Aldea, MD, Mathew R. Williams, MD, Raj Makkar, MD, Lars G. Svensson, MD, PhD, James M. McCabe, MD, Larry S. Dean, MD, Samir Kapadia, MD, David J. Cohen, MD, Augusto D. Pichard, MD, Wilson Y. Szeto, MD, Howard C. Herrmann, MD, Chandan Devireddy, MD, Bradley G. Leshnower, MD, Gorav Ailawadi, MD, Hersh S. Maniar, MD, Rebecca T. Hahn, MD, Martin B. Leon, MD, Michael Mack, MD  The Annals of Thoracic Surgery  Volume 100, Issue 3, Pages (September 2015) DOI: /j.athoracsur Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Age distributions of study cohorts (% in each year). (A) Transfemoral transcatheter aortic valve replacement (TF-TAVR). (B) Transapical transcatheter aortic valve replacement (TA-TAVR). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Prosthetic valve hemodynamics after transcatheter aortic valve replacement (TAVR). (A) Box-and-whiskers plots depicting the distribution of transvalvular aortic mean gradient at discharge, 30 days, and 6 months after transfemoral (TF)-TAVR. Horizontal bars within the boxes indicate median; top and bottom of the boxes indicate 75th and 25th percentiles. Whiskers extend to 1.5 times the interquartile range. (B) Percent of TF-TAVR patients in each paravalvular leak grade at discharge, 30 days, and 6 months. (C) Box-and-whiskers plots depicting the distribution of transvalvular aortic mean gradient at discharge, 30 days, and 6 months after transapical (TA)-TAVR. Format is as in (A). (D) Percent of TA-TAVR patients in each paravalvular leak grade at discharge, 30 days, and 6 months. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Functional health status and quality of life after transcatheter aortic valve replacement (TAVR). (A) Percent of transfemoral (TF)-TAVR patients in each New York Heart Association (NYHA) functional class at discharge, 30 days, and 6 months. (B) Quality of life measures at baseline, then 1 month, 6 months, and 1 year after TF-TAVR. Horizontal bars within the boxes indicate median; top and bottom of the boxes indicate 75th and 25th percentiles. Whiskers extend to 1.5 times the interquartile range. Outliers beyond the whiskers are plotted as points. (C) Percent of transapical (TA)-TAVR patients in each New York Heart Association (NYHA) functional class at discharge, 30 days, and 6 months. (D) Quality of life measures at baseline, then 1 month, 6 months, and 1 year after TA-TAVR. Format is as in (B). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Stroke after transcatheter aortic valve replacement (TAVR) stratified by transfemoral (TF)-TAVR versus transapical (TA)-TAVR. Each symbol represents a stroke. Vertical bars are confidence intervals of Kaplan-Meier estimates equivalent to ±1 standard error and solid lines enclosed within dashed 68% confidence bands equivalent to ±1 standard error represent parametric estimates. Numbers below the x axis are patients at risk. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Death after transcatheter aortic valve replacement (TAVR) stratified by transfemoral (TF)-TAVR versus transapical (TA)-TAVR, referenced to that expected in an age-sex-race–matched US population (– • – lines). Each symbol represents a death. Vertical bars are confidence intervals of Kaplan-Meier estimates equivalent to ±1 standard error and solid lines enclosed within dashed 68% confidence bands equivalent to ±1 standard error represent parametric estimates. Numbers below the x axis are patients at risk. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

7 Fig E1A The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

8 Fig E1B The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

9 Fig E2A The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

10 Fig E2B The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

11 Fig E3A The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

12 Fig E3B The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

13 Fig E4A The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

14 Fig E4B The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Download ppt "Vinod H. Thourani, MD, Hanna A"

Similar presentations

Volume 385, Issue 9986, Pages (June 2015)

Volume 385, Issue 9986, Pages (June 2015)
Volume 387, Issue 10034, Pages (May 2016)

Volume 387, Issue 10034, Pages (May 2016)
One-Year Outcomes of Transcatheter Aortic Valve Replacement in Patients With End- Stage Renal Disease  Daniel P. O’Hair, MD, Tanvir K. Bajwa, MD, Stanley.

One-Year Outcomes of Transcatheter Aortic Valve Replacement in Patients With End- Stage Renal Disease  Daniel P. O’Hair, MD, Tanvir K. Bajwa, MD, Stanley.
Moderate Tricuspid Regurgitation With Left-Sided Degenerative Heart Valve Disease: To Repair or Not to Repair?  Jose L. Navia, MD, Nicolas A. Brozzi,

Moderate Tricuspid Regurgitation With Left-Sided Degenerative Heart Valve Disease: To Repair or Not to Repair?  Jose L. Navia, MD, Nicolas A. Brozzi,
High Risk of Prosthetic Valve Endocarditis and Death After Valve Replacement Operations in Dialysis Patients  Danielle K. Farrington, MD, Patrick D. Kilgo,

High Risk of Prosthetic Valve Endocarditis and Death After Valve Replacement Operations in Dialysis Patients  Danielle K. Farrington, MD, Patrick D. Kilgo,
Characterization and Importance of Air Leak After Lobectomy

Characterization and Importance of Air Leak After Lobectomy
The Association of Transcatheter Aortic Valve Replacement Availability and Hospital Aortic Valve Replacement Volume and Mortality in the United States 

The Association of Transcatheter Aortic Valve Replacement Availability and Hospital Aortic Valve Replacement Volume and Mortality in the United States 
Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Graft Operation: A PARTNER Trial Subgroup Analysis 

Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Graft Operation: A PARTNER Trial Subgroup Analysis 
Transcatheter and Surgical Aortic Valve Replacement in Dialysis Patients: A Propensity- Matched Comparison  Dale M. Kobrin, BA, Fenton H. McCarthy, MD,

Transcatheter and Surgical Aortic Valve Replacement in Dialysis Patients: A Propensity- Matched Comparison  Dale M. Kobrin, BA, Fenton H. McCarthy, MD,
Moderate Tricuspid Regurgitation With Left-Sided Degenerative Heart Valve Disease: To Repair or Not to Repair?  Jose L. Navia, MD, Nicolas A. Brozzi,

Moderate Tricuspid Regurgitation With Left-Sided Degenerative Heart Valve Disease: To Repair or Not to Repair?  Jose L. Navia, MD, Nicolas A. Brozzi,
A comprehensive review of the PARTNER trial

A comprehensive review of the PARTNER trial
Current Status of Endovascular Training for Cardiothoracic Surgery Residents in the United States  Panos N. Vardas, MD, Ada C. Stefanescu Schmidt, MD,

Current Status of Endovascular Training for Cardiothoracic Surgery Residents in the United States  Panos N. Vardas, MD, Ada C. Stefanescu Schmidt, MD,
Long-Term Outcomes After Isolated Aortic Valve Replacement in Octogenarians: A Modern Perspective  Vinod H. Thourani, MD, Richard Myung, MD, Patrick Kilgo,

Long-Term Outcomes After Isolated Aortic Valve Replacement in Octogenarians: A Modern Perspective  Vinod H. Thourani, MD, Richard Myung, MD, Patrick Kilgo,
Hancock II Bioprosthesis for Aortic Valve Replacement: The Gold Standard of Bioprosthetic Valves Durability?  Tirone E. David, MD, Susan Armstrong, MS,

Hancock II Bioprosthesis for Aortic Valve Replacement: The Gold Standard of Bioprosthetic Valves Durability?  Tirone E. David, MD, Susan Armstrong, MS,
Current Effectiveness and Risks of Isolated Septal Myectomy for Hypertrophic Obstructive Cardiomyopathy  Nicholas G. Smedira, MD, Bruce W. Lytle, MD,

Current Effectiveness and Risks of Isolated Septal Myectomy for Hypertrophic Obstructive Cardiomyopathy  Nicholas G. Smedira, MD, Bruce W. Lytle, MD,
Beyond the Aortic Root: Staged Open and Endovascular Repair of Arch and Descending Aorta in Patients With Connective Tissue Disorders  Eric E. Roselli,

Beyond the Aortic Root: Staged Open and Endovascular Repair of Arch and Descending Aorta in Patients With Connective Tissue Disorders  Eric E. Roselli,
Endovascular versus open elephant trunk completion for extensive aortic disease  Eric E. Roselli, MD, Sreekumar Subramanian, MD, Zhiyuan Sun, BS, Jahanzaib.

Endovascular versus open elephant trunk completion for extensive aortic disease  Eric E. Roselli, MD, Sreekumar Subramanian, MD, Zhiyuan Sun, BS, Jahanzaib.
Transcatheter or Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Grafting  John V. Conte, MD, Thomas G. Gleason, MD, Jon.

Transcatheter or Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Grafting  John V. Conte, MD, Thomas G. Gleason, MD, Jon.
Mitral Valve Surgery in the Adult Marfan Syndrome Patient

Mitral Valve Surgery in the Adult Marfan Syndrome Patient
Improved Mitral Valve Performance After Transapical Aortic Valve Implantation  Martin Haensig, MD, David Michael Holzhey, MD, PhD, Michael Andrew Borger,

Improved Mitral Valve Performance After Transapical Aortic Valve Implantation  Martin Haensig, MD, David Michael Holzhey, MD, PhD, Michael Andrew Borger,

Similar presentations

Ads by Google