1. Volume 88, Issue 5, Pages 1126-1134 (November 2015)
Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults 
Pranav S. Garimella, Mary L. Biggs, Ronit Katz, Joachim H. Ix, Michael R. Bennett, Prasad Devarajan, Bryan R. Kestenbaum, David S. Siscovick, Majken K. Jensen, Michael G. Shlipak, Paulo H.M. Chaves, Mark J. Sarnak 
Kidney International 
Volume 88, Issue 5, Pages (November 2015)
DOI: /ki
Copyright © 2015 International Society of Nephrology Terms and Conditions

2. Figure 1
Population sampling from within the Cardiovascular Health Study (CHS). Rectangle: all CHS participants at 1996–1997 visit. Large circle: random subcohort. Black circle: participants included as controls in the case–control study for the chronic kidney disease (CKD) progression outcome. Light gray area: participants included as cases in the case–control study for the CKD progression. Dark gray area: participants included in the case–cohort study for the incident end-stage renal disease (ESRD) outcome. CVD, cardiovascular disease; HF, heart failure.
Kidney International  , DOI: ( /ki )
Copyright © 2015 International Society of Nephrology Terms and Conditions

3. Figure 2
Distribution of urine uromodulin (UMOD) levels in 958 community-living elderly participants in the Cardiovascular Health Study.
Kidney International  , DOI: ( /ki )
Copyright © 2015 International Society of Nephrology Terms and Conditions

4. Figure 3
Spline regression plots of urinary uromodulin (UMOD) and clinical outcomes. Left to right and top to bottom: progressive glomerular filtration rate (GFR) decline, incident cardiovascular disease (CVD), heart failure (HF), and mortality. Each model was fitted using a restricted cubic spline function for urinary uromodulin (uUMOD). In each plot, the solid line represents the point estimate and the dotted lines represent 95% confidence intervals. Observations in the highest 2.5% of the distribution were excluded to minimize the influence of extreme values.
Kidney International  , DOI: ( /ki )
Copyright © 2015 International Society of Nephrology Terms and Conditions