1. S3: HEREDITY E5: PEDIGREES
Objective: Infer genotypes based on phenotypes in a pedigree
GRAB YOUR NOTEBOOK and the green paper from the front

2. I. HUMAN GENETICS AND PEDIGREES

3. I. HUMAN GENETICS AND PEDIGREES
Human genetics follows the patterns seen in sexually reproducing organisms

4. I. HUMAN GENETICS AND PEDIGREES
Human genetics follows the patterns seen in sexually reproducing organisms
B. Females can carry sex-linked genetic disorders.

5. I. HUMAN GENETICS AND PEDIGREES
Human genetics follows the patterns seen in sexually reproducing organisms
B. Females can carry sex-linked genetic disorders.
Males (XY) express all of their sex-linked genes.

6. I. HUMAN GENETICS AND PEDIGREES
Human genetics follows the patterns seen in sexually reproducing organisms
B. Females can carry sex-linked genetic disorders.
Males (XY) express all of their sex-linked genes.
2. Males tend to show sex-linked disorders more than females

8. C. A Pedigree is a chart for tracing genes in a family.

9. C. A Pedigree is a chart for tracing genes in a family.
Phenotypes are used to infer genotypes

10. C. A Pedigree is a chart for tracing genes in a family.
Phenotypes are used to infer genotypes
2. Autosomal genes show different patterns than sex-linked genes.

11. How to read a pedigree:
□ = male

12. How to read a pedigree:
□ = male
○ = female

13. Horizontal lines between a male and female: marriage
How to read a pedigree:
□ = male
○ = female
Horizontal lines between a male and female: marriage

14. Horizontal lines between a male and female: marriage
How to read a pedigree:
□ = male
○ = female
Horizontal lines between a male and female: marriage
Horizontal lines above males and females: siblings

15. Horizontal lines between a male and female: marriage
How to read a pedigree:
□ = male
○ = female
Horizontal lines between a male and female: marriage
Horizontal lines above males and females: siblings
Vertical lines: offspring

16. Horizontal lines between a male and female: marriage
How to read a pedigree:
□ = male
○ = female
Horizontal lines between a male and female: marriage
Horizontal lines above males and females: siblings
Vertical lines: offspring
Colored in shapes: show the phenotype

17. Horizontal lines between a male and female: marriage
How to read a pedigree:
□ = male
○ = female
Horizontal lines between a male and female: marriage
Horizontal lines above males and females: siblings
Vertical lines: offspring
Colored in shapes: show the phenotype
Half colored in shapes: carrier

18. Example: Autosomal Pedigree
How many kids did the couple in generation I have?
How many of those kids got married?
How many boys/girls have the disease?
How does this pedigree show this disease is autosomal?
Is this a dominant or recessive disease? How do you know?
Write in the genotypes for each individual.

19. How do autosomal dominant traits show up different on a pedigree than autosomal recessive traits?

20. Example: Sex Linked Pedigree
How many kids did the couple in generation I have?
How many boys/girls have the disease?
How does this pedigree show this disease is sex-linked?
Write in the genotypes for each individual
Is it possible for a female to have a sex linked disease? What would the parents’ genotypes have to be?

22. PEDIGREE WORKSHEET
GRAB A PEDIGREE WORKSHEET AND COMPLETE IT IN YOUR LAB NOTEBOOK
RETURN THE SHEET BEFORE THE BELL