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Anaplastic Lymphoma Kinase Translocation: A Predictive Biomarker of Pemetrexed in Patients with Non-small Cell Lung Cancer  Jeong-Ok Lee, MD, Tae Min.

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Presentation on theme: "Anaplastic Lymphoma Kinase Translocation: A Predictive Biomarker of Pemetrexed in Patients with Non-small Cell Lung Cancer  Jeong-Ok Lee, MD, Tae Min."— Presentation transcript:

1 Anaplastic Lymphoma Kinase Translocation: A Predictive Biomarker of Pemetrexed in Patients with Non-small Cell Lung Cancer  Jeong-Ok Lee, MD, Tae Min Kim, MD, Se-Hoon Lee, MD, Dong-Wan Kim, MD, Soyeon Kim, MS, Yoon-Kyung Jeon, MD, Doo Hyun Chung, MD, Woo-Ho Kim, MD, Young Tae Kim, MD, Seok-Chul Yang, MD, Young Whan Kim, MD, Dae Seog Heo, MD, Yung-Jue Bang, MD  Journal of Thoracic Oncology  Volume 6, Issue 9, Pages (September 2011) DOI: /JTO.0b013e fc2 Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Kaplan-Meier plot of time to progression in all patients.
Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e fc2) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Kaplan-Meier plots of time to progression in patients treated with second-line pemetrexed (A) and in those treated with third-line pemetrexed and beyond (B). Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e fc2) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 In vitro cytotoxicity of pemetrexed (A) and thymidylate synthase mRNA level (B) in non-small cell lung cancer cells. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e fc2) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

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