Presentation is loading. Please wait.

Presentation is loading. Please wait.

In acute lung injury, inhaled nitric oxide improves ventilation-perfusion matching, pulmonary vascular mechanics, and transpulmonary vascular efficiency 

Similar presentations


Presentation on theme: "In acute lung injury, inhaled nitric oxide improves ventilation-perfusion matching, pulmonary vascular mechanics, and transpulmonary vascular efficiency "— Presentation transcript:

1 In acute lung injury, inhaled nitric oxide improves ventilation-perfusion matching, pulmonary vascular mechanics, and transpulmonary vascular efficiency  Neal D. Hillman, MDb, Jon N. Meliones, MDa, Donald R. Black, MDa, Damian M. Craig, MSb, Ira M. Cheifetz, MDa, Peter K. Smith, MDb  The Journal of Thoracic and Cardiovascular Surgery  Volume 110, Issue 3, Pages (September 1995) DOI: /S (95) Copyright © 1995 Mosby, Inc. Terms and Conditions

2 Fig. 1 The effect of inhaled NO on ventilation perfusion matching. NO significantly improved ventilation-perfusion matching, but no dose-response relationship was noted. When NO was discontinued, ventilation-perfusion matching returned to baseline levels. *p < 0.05 versus 0 ppm. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

3 Fig. 2 NO decreased PA pressure, which returned to baseline levels on discontinuation of NO. No dose-response relationship was noted. *p < 0.05 versus 0 ppm. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

4 Fig. 3 NO significantly improved transpulmonary vascular efficiency (TVE = pulmonary blood flow/total RV power). *p < 0.05 versus 0 ppm. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions

5 Fig. 4 Inhaled NO resulted in a significant increase in Pao2. When NO was discontinued, Pao2 returned to baseline values. *p < 0.05 versus 0 ppm. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (95) ) Copyright © 1995 Mosby, Inc. Terms and Conditions


Download ppt "In acute lung injury, inhaled nitric oxide improves ventilation-perfusion matching, pulmonary vascular mechanics, and transpulmonary vascular efficiency "

Similar presentations


Ads by Google