1. Enhancement of the leukocyte–endothelial cell interaction in collecting venules of skeletal muscle by protamine 
Helmut Habazettl, MDa, Vladimir Martinek, MDa, Brigitte Vollmar, MDa, Peter Conzen, MDb 
The Journal of Thoracic and Cardiovascular Surgery 
Volume 113, Issue 4, Pages (April 1997)
DOI: /S (97)
Copyright © 1997 Mosby, Inc. Terms and Conditions

2. Fig. 1
Systemic leukocyte counts from arterial blood were determined 1 minute before and 2, 5, 15, and 25 minutes after protamine injection (↓↓). Heparin was given 4 minutes before protamine (↓). Study groups: Control animals (n = 10) received neither heparin nor protamine but equal volumes of saline solution; the protamine group (group P, n = 9) was given saline solution at −4 minutes and protamine at time zero. H-P,v animals (n = 9) received heparin and protamine, both intravenously; H-P,a hamsters (n = 9) were given an intravenous injection of heparin, followed by protamine administration into the aorta. All data are mean ± standard error of the mean; #p < 0.05, all experimental groups versus the control group.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) )
Copyright © 1997 Mosby, Inc. Terms and Conditions

3. Fig. 2
The leukocyte discharge concentration, that is, an estimation of the concentration of leukocytes in the blood passing the venules under investigation (one per animal), is given in percent of baseline immediately before protamine. ↓, Injection of heparin; ↓↓, injection of protamine. Microvascular data were obtained in one venule of each hamster before heparin (−7), after heparin (−3), and 0.5, 2, 4.5, 7, 13, and 23 minutes after protamine. For abbreviations of study groups see Fig. 1. All data are mean ± standard error of the mean; #p < 0.05, all experimental groups versus the control group.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) )
Copyright © 1997 Mosby, Inc. Terms and Conditions

4. Fig. 3
The number of leukocytes rolling along the endothelium of the venules under investigation (one per animal) is given in percent of all nonadherent leukocytes. ↓, Heparin; ↓↓, protamine injection. For definition of study groups see Fig. 1. All data are mean ± standard error of the mean; *p < 0.05, H-P,v versus the control group; #p < 0.05, all experimental groups versus the control group.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) )
Copyright © 1997 Mosby, Inc. Terms and Conditions

5. Fig. 4
The number of leukocytes adhering to the endothelium of the venules under investigation (one per animal) is given in cells per square millimeter of endothelial surface area. ↓, Heparin; ↓↓, protamine injection. For definition of study groups see Fig. 1. All data are mean ± standard error of the mean; *p < 0.05, H-P,a versus the control group; #p < 0.05, all experimental groups versus the control group.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) )
Copyright © 1997 Mosby, Inc. Terms and Conditions

6. Fig. 5
The tissue concentration of MPO was determined in different organs of 20 separate hamsters 2 minutes after injection of saline solution (control, n = 10) or of protamine (protamine, n = 10). All data are mean ± standard error of the mean; #p < 0.05, protamine group versus control group.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (97) )
Copyright © 1997 Mosby, Inc. Terms and Conditions