Presentation is loading. Please wait.

Presentation is loading. Please wait.

Y. Sun, N. Haines, A. Roberts, M. Ruffolo, D. Mauerhan, J. Ingram, M

Published byOliver Lindholm Modified over 5 years ago

Similar presentations

Presentation on theme: "Y. Sun, N. Haines, A. Roberts, M. Ruffolo, D. Mauerhan, J. Ingram, M"— Presentation transcript:

1 Phosphocitrate reduced cartilage degeneration in non-calcification induced osteoarthritis 
Y. Sun, N. Haines, A. Roberts, M. Ruffolo, D. Mauerhan, J. Ingram, M. Cox, E. Hanley  Osteoarthritis and Cartilage  Volume 23, Pages A395-A396 (April 2015) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1. Radiographs of the medial meniscus
Figure 1. Radiographs of the medial meniscus. Left: Radiograph of medial meniscus of the left knee (non-operated knee) of the guinea pigs. The anterior horn was severely calcified or ossified (arrow). Right: Radiographs of medial meniscus of right knee (surgery performed knee) of the guinea pigs. The severely ossified anterior horn was absent, removing by the partial-meniscectomy surgery (arrow). Osteoarthritis and Cartilage  , A395-A396DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2. Mean histological scores of the tibia plateaus
Figure 2. Mean histological scores of the tibia plateaus. Left bar group: Mean histological scores of the medial tibia plateaus of the rights knees in the untreated and PC-treated guinea pigs. Right bar group: Mean histological scores of the lateral tibia plateaus of the right knees in the untreated and PC-treated guinea pigs. * = P < 0.05 PC-treated versus the untreated guinea pigs. Osteoarthritis and Cartilage  , A395-A396DOI: ( /j.joca ) Copyright © Terms and Conditions

4 Figure 3. Cartilage thickness
Figure 3. Cartilage thickness. Left: thickness of the medial tibia cartilage in the untreated guinea pigs. Right: thickness of the medial tibia cartilage in the PC-treated guinea pigs. Osteoarthritis and Cartilage  , A395-A396DOI: ( /j.joca ) Copyright © Terms and Conditions

5 Figure 4. Immunostaining scores. Left bar group: MMP-15 immunostaining
Figure 4. Immunostaining scores. Left bar group: MMP-15 immunostaining. Middle bar group: ADAMTS5 immunostaining. Right bar group: CCL-5 immunostaining. Osteoarthritis and Cartilage  , A395-A396DOI: ( /j.joca ) Copyright © Terms and Conditions

Download ppt "Y. Sun, N. Haines, A. Roberts, M. Ruffolo, D. Mauerhan, J. Ingram, M"

Similar presentations

Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment  R. Moyer, W. Wirth, F. Eckstein  Osteoarthritis.

Anatomical alignment, but not goniometry, predicts femorotibial cartilage loss as well as mechanical alignment  R. Moyer, W. Wirth, F. Eckstein  Osteoarthritis.
The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,
Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study 

Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study 
Micro-CT bone structure evaluation in the Pond-Nuki dog model

Micro-CT bone structure evaluation in the Pond-Nuki dog model
Where does meniscal damage progress most rapidly

Where does meniscal damage progress most rapidly
Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative  M. Hakky, M. Jarraya,

Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative  M. Hakky, M. Jarraya,
Extraction of anatomical landmarks and axis for 3D coordinate system construction of femur and tibia bone models  X. Cui, H. Kim, S. Li, K.-S. Kwack,

Extraction of anatomical landmarks and axis for 3D coordinate system construction of femur and tibia bone models  X. Cui, H. Kim, S. Li, K.-S. Kwack,
Cartilage Thickness, Denudation and Kl Grade: A Study of Medial Femorotibial Joints in 8,890 Knees from the Osteoarthritis Initiative  G. Guillard, G.R.

Cartilage Thickness, Denudation and Kl Grade: A Study of Medial Femorotibial Joints in 8,890 Knees from the Osteoarthritis Initiative  G. Guillard, G.R.
Non-destructive evaluation of articular cartilage defects using near-infrared (NIR) spectroscopy in osteoarthritic rat models and its direct relation.

Non-destructive evaluation of articular cartilage defects using near-infrared (NIR) spectroscopy in osteoarthritic rat models and its direct relation.
Pelvic movements are restored to reference values during stair climbing but not during stepping one year after uni-compartmental knee arthroplasty – A.

Pelvic movements are restored to reference values during stair climbing but not during stepping one year after uni-compartmental knee arthroplasty – A.
ADAMTS5−/− mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage.

ADAMTS5−/− mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage.
A sex-specific association between incident radiographic osteoarthritis of hip or knee and incident peripheral arterial calcifications: 8-year prospective.

A sex-specific association between incident radiographic osteoarthritis of hip or knee and incident peripheral arterial calcifications: 8-year prospective.
Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA  J.L. Huebner, K.A. Johnson,

Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA  J.L. Huebner, K.A. Johnson,
A sex-specific association between the development of radiographic osteoarthritis of the hip or knee and development of peripheral arterial calcifications:

A sex-specific association between the development of radiographic osteoarthritis of the hip or knee and development of peripheral arterial calcifications:
Spatial and temporal changes of subchondral bone proceed to microscopic articular cartilage degeneration in guinea pigs with spontaneous osteoarthritis 

Spatial and temporal changes of subchondral bone proceed to microscopic articular cartilage degeneration in guinea pigs with spontaneous osteoarthritis 
Prospective economic evaluation of the costs for medications and nutraceuticals in knee osteoarthritis  M. Chung, N. Zhao, J.B. Wong, C. Wang  Osteoarthritis.

Prospective economic evaluation of the costs for medications and nutraceuticals in knee osteoarthritis  M. Chung, N. Zhao, J.B. Wong, C. Wang  Osteoarthritis.
Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion  A.V.

Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion  A.V.
Does a yoga-strengthening program for women with knee osteoarthritis have an effect on gait patterns? An investigation with principal components analysis 

Does a yoga-strengthening program for women with knee osteoarthritis have an effect on gait patterns? An investigation with principal components analysis 
Parathyroid hormone(1-34) exhibits more comprehensive effects than celecoxib in cartilage metabolism and maintaining subchondral bone micro-architecture.

Parathyroid hormone(1-34) exhibits more comprehensive effects than celecoxib in cartilage metabolism and maintaining subchondral bone micro-architecture.
Sensitivity to Change of 3D Meniscal Measures in Rapidly Progressing Knee Osteoarthritis and Association With Radiographic Joint Space Width Loss  M.

Sensitivity to Change of 3D Meniscal Measures in Rapidly Progressing Knee Osteoarthritis and Association With Radiographic Joint Space Width Loss  M.

Similar presentations

Ads by Google