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THE CELL CYCLE
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All organisms have a life cycle:
birth growth reproduction death
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Within all organisms, cells are also “born”, grow, reproduce/divide, and die.
CELL TYPE LIFE SPAN Lining of the intestine 4-5 days Skin cell 2 weeks Red blood cell 4 months Liver cell days Brain cells 100 years Brain cells do not divide… you are born with all your brain cells you will ever have!
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Cell Cycle - cells are born - cells grow and work - cells divide to make new cells - cells die
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CANCER: Uncontrolled Cell Growth
a disorder in which body cells lose the ability to control cell growth and cell division. Cancer cells do not respond to signals that regulate their cell cycle; As a result cells divide uncontrollably.
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Before a cell divides, it must….
The cell copies its DNA . At the end of this stage, the nucleus contains two complete sets of DNA.
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During DNA replication…..
C G & T A G C
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Perform DNA replication
on the following DNA strand: T G A T T C G T A G C C A A C T A A G C A T C G G T
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Perform DNA replication
G A C --- A C T G
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Perform DNA replication
G A C --- A T --- A C T G --- C G --- --- T A --- --- A T --- --- C --- G --- T A --- G --- --- C --- T --- A
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Perform DNA replication
G A C --- A C T G
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Perform DNA replication
G A C --- A T --- A C T G --- C G --- --- T A --- --- A T --- --- C --- G --- T A --- G --- --- C --- T --- A
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DNA Replication
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DNA Replication
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CELL DIVISION MITOSIS
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Why do cells undergo mitosis?
To make new cells… To replace old or dead cells To replace cells destroyed by injury Skin cells
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for growth and development.
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to produce a new individual --- asexual reproduction
the production of genetically identically offspring from a single parent…a clone.
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MITOSIS pmat There are four phases in mitosis: 1. prophase
2. metaphase 3. anaphase 4. telophase pmat
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Before mitosis, DNA must be… duplicated
cell DNA Replication cell
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Prophase The duplicated chromosomes condense. cell
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Metaphase Chromosomes line up along the middle of the cell.
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Anaphase Chromosomes are pulled apart and
move to opposite ends of the cell.
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Telophase The chromosomes gather at opposite poles
of the cell forming two nuclei.
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Cytokinesis The cytoplasm divides, forming two identical cells.
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telophase
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cytokinesis
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metaphase
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anaphase
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interphase
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prophase
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MEIOSIS
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Why do cells undergo meiosis?
To make egg and sperm for sexual reproduction gametes Eggs are made in the ________ ovaries Sperm are made in the _______ testes
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Body Cells vs Gametes 46 chromosomes 23 chromosomes Homologous pairs
Mom & Dad pairs Homologous pairs Unpaired chromosomes Diploid cell Haploid cell
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A Body cell A diploid cell Homologous pairs
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A sex cell A Gamete --- _________ A haploid cell Half the chromosomes
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MEIOSIS 1 4 2n diploid cell haploid cell (gametes) n n n n 24
chromosomes 12 chromosomes
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Interphase Meiosis I Meiosis II DNA Replication
Homologous chromosomes separate DNA/Chromosomes duplicate Sister chromatids separate
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MEIOSIS There are eight phases in meiosis: 1. prophase I
2. metaphase I 3. anaphase I 4. telophase I Meiosis I 5. prophase II 6. metaphase II 7. anaphase II 8. telophase II Meiosis II
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1. Prophase I Crossing-over Homologous chromosomes pair up
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2. Metaphase I middle
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3. Anaphase I Homologous chromosomes separate middle
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4. Telophase I cytokinesis
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5. Prophase II
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6. Metaphase II middle
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7. Anaphase II middle
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8. Telophase II End result: Four haploid cell (n)
Each of the four cells is genetically different from each other and from the parent cell.
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& Asexual reproduction
MITOSIS vs MEIOSIS Makes body cells & Asexual reproduction Makes gametes (egg & sperm) 24 12 12 24 24 24 12 12 1 cell 2 cell 1 cell 4 cell 24 chromosomes 24 chromosomes 24 chromosomes 12 chromosomes Asexual reproduction produces identical offspring …no genetic diversity Sexual reproduction produces genetical different offspring …large genetic diversity
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