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Relevance of Platinum-Sensitivity Status in Relapsed/Refractory Extensive-Stage Small- Cell Lung Cancer in the Modern Era: A Patient-Level Analysis of.

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Presentation on theme: "Relevance of Platinum-Sensitivity Status in Relapsed/Refractory Extensive-Stage Small- Cell Lung Cancer in the Modern Era: A Patient-Level Analysis of."— Presentation transcript:

1 Relevance of Platinum-Sensitivity Status in Relapsed/Refractory Extensive-Stage Small- Cell Lung Cancer in the Modern Era: A Patient-Level Analysis of Southwest Oncology Group Trials  Primo N. Lara, MD, James Moon, MS, Mary W. Redman, PhD, Thomas J. Semrad, MD, Karen Kelly, MD, Jeffrey W. Allen, MD, Barbara J. Gitlitz, MD, Philip C. Mack, PhD, David R. Gandara, MD  Journal of Thoracic Oncology  Volume 10, Issue 1, Pages (January 2015) DOI: /JTO Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Kaplan–Meier curves for crude progression-free and overall survival, stratified by platinum-sensitivity status (unadjusted for clinical variables). Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Recursive partitioning analysis of platinum-treated small-cell lung cancer. LDH, lactate dehydrogenase; OS, overall survival. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Kaplan Meier survival curves for high, intermediate, and poor risk groups. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions


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