1. Folate and Methylenetetrahydrofolate Reductase Polymorphisms: New Nutritional and Genetic Risk Factors for Pancreatic Cancer? 
Young-In Kim, MD 
Clinical Gastroenterology and Hepatology 
Volume 3, Issue 8, Pages (August 2005)
DOI: /S (05)
Copyright © 2005 American Gastroenterological Association Terms and Conditions

2. Figure 1
Simplified scheme of folate metabolism. MTHFR catalyzes the irreversible conversion of 5,10-methyleneTHF to 5-methylTHF. B12, vitamin B12; DHFR, dihydrofolate reductase; CH3, methyl group; CpG, cytosine-guanine dinucleotide sequence; SAH, S-adenosylhomocysteine.
Clinical Gastroenterology and Hepatology 2005 3, DOI: ( /S (05) )
Copyright © 2005 American Gastroenterological Association Terms and Conditions