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Treatment of severe hyponatremia

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1 Treatment of severe hyponatremia
Dr Peter Gross  Kidney International  Volume 60, Issue 6, Pages (December 2001) DOI: /j x Copyright © 2001 International Society of Nephrology Terms and Conditions

2 Figure 1 Course of the serum sodium concentration presented over the first 11 days of hospitalization. The horizontal bars at the top of the diagram indicate the treatment given to the patient. The normal range of serum sodium concentration of the laboratory was 136mmol/L to 149mmol/L. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

3 Figure 2 Axial computer tomographic (CT) scans of the brain showing a normal study (A) and brain edema (B). Note the diminution of the size of the ventricles in B; in addition, the sulci of the brain are no longer demonstrable in panel B (CTs were kindly provided by Dr. V. Hänig, U.K.D., Dresden, Germany). Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

4 Figure 3 Total increase of the serum sodium concentration over the first 7 days of treatment of severe hyponatremia. Symbols are: () 12 patients with CPM; (□), 9 patients without CPM. (Reproduced with permission from Williams & Wilkins,36 Annals of Neurology 11:128–135, 1982.) Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

5 Figure 4 Left: Saggital T2-weighted nuclear magnetic resonance (NMR) section showing an oval-shaped region of discrete hyperintensity in the center of the pons 9 days after onset of clinical symptoms following correction of hyponatremia. Right: follow-up examination 23 days after onset of clinical symptoms revealing a distinct rise in signal intensity. (Reproduced with permission from Springer-Verlag,38 Eur Radiol 6:177–183, 1996.) Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

6 Kidney International 2001 60, 2417-2427DOI: (10. 1046/j. 1523-1755
Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions


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