1. SEE LOWER CONCENTRATIONS WITH THE NQAD DETECTOR
Application note # QAN-0087 ™
APPLICATION NOTES
CHROMATOGRAMS
PARAMETERS
4.9 mV
NQAD
GAS: Air
FILTER: 1.3 sec
GAIN: 1X
EVAPORATION TEMP: 35C
ELSD
GAS: Nitrogen, 1.5 L/min
GAIN: 1
EVAPORATION TEMP: 40C
HPLC
MOBILE PHASE: 25:75 ACN:Water with 0.2% TFA
NQAD, 16 ng
S/N = 167
ELSD, 16 ng
S/N < 3
FLOW RATE: 1.00 mL/min
COLUMN: Phenomenex Kinetex C18, 150 x 4.6, 2.6 u
COLUMN TEMP: Ambient
INJECTION VOLUME :1 µL
CONCENTRATION: 16 ng on column
ANALYTE: Ephedrine
Demonstrates better sensitivity than ELSD
4.3
0.00
1.00
2.00
3.0
QUANT TECHNOLOGIES, LLC
TH Lane NE
Blaine, MN, USA
Note: This application was run at Quant Technologies on a single ELSD and may not be representative of all ELSD’s. 1