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Comparison of pattern of breathing with other measures of induction of anaesthesia, using propofol, methohexital, and sevoflurane†  T.L. Strickland, G.B.

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Presentation on theme: "Comparison of pattern of breathing with other measures of induction of anaesthesia, using propofol, methohexital, and sevoflurane†  T.L. Strickland, G.B."— Presentation transcript:

1 Comparison of pattern of breathing with other measures of induction of anaesthesia, using propofol, methohexital, and sevoflurane†  T.L. Strickland, G.B. Drummond  British Journal of Anaesthesia  Volume 86, Issue 5, Pages (May 2001) DOI: /bja/ Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 A good example of the change in respiratory pattern during induction of anaesthesia. Inspiratory flow is down. Swallowing during expiration (marked S) occurs in two breaths preceding the onset of a sudden change in frequency and pattern of flow. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 Mean time with sd to end point for the three agents. Propofol, open column; methohexital, shaded column; sevoflurane, filled column. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 Cumulative response curves for the three agents. The responses shown in these panels are in sequence: open square symbols, breathing change; filled triangles, cessation of tapping; open diamonds, loss of arm tone; and filled circles, loss of grip. The loss of lash reflex overlaps some of these curves and is, therefore, shown as continuous lines. Six patients did not lose the lash reflex. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

5 Fig 4 Cumulative response curves for the three agents, using a logit scale, for the loss of arm tone. Propofol, open circles; methohexital, closed triangles; and sevoflurane, open squares. The plots are straight, diverge, and do not overlap. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

6 Fig 5 Cumulative response curves for the three agents, using a logit scale, for the loss of the lash reflex. Symbols as in Figure 4. The plots are straight, but do not diverge, and those for methohexital and propofol overlap. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions


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