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L.M. Ferguson, G.B. Drummond  British Journal of Anaesthesia 

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Presentation on theme: "L.M. Ferguson, G.B. Drummond  British Journal of Anaesthesia "— Presentation transcript:

1 Acute effects of fentanyl on breathing pattern in anaesthetized subjects 
L.M. Ferguson, G.B. Drummond  British Journal of Anaesthesia  Volume 96, Issue 3, Pages (March 2006) DOI: /bja/ael011 Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 The breathing system used. The fresh gas flow was set at 15 litre min−1. British Journal of Anaesthesia  , DOI: ( /bja/ael011) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 Changes in (a) end-tidal partial pressure of carbon dioxide and (b) end-tidal concentration of sevoflurane after drug administration. British Journal of Anaesthesia  , DOI: ( /bja/ael011) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 Effects of fentanyl 0.5 μg kg−1 on breathing pattern. The values of duration of inspiration (T1), expiration (TE) and tidal volume (VT) increased significantly (all P<0.01, Friedman test). British Journal of Anaesthesia  , DOI: ( /bja/ael011) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

5 Fig 4 Summary spirogram of the effects of fentanyl on the breathing pattern. British Journal of Anaesthesia  , DOI: ( /bja/ael011) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

6 Fig 5 The inspiratory flow patterns of the individual subjects, before (dotted line) and 240 s after (continuous line) fentanyl. In all subjects the initial rate of increase of flow rate was reduced. British Journal of Anaesthesia  , DOI: ( /bja/ael011) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

7 Fig 6 Individual changes in the relationship between tidal volume and duration of inspiration. The filled symbol represents the control condition, and the line represents the changes after fentanyl. In one subject, a reciprocal relationship was evident: in the other subjects there was either little change or a proportional change in both values (a positive slope of the plot). British Journal of Anaesthesia  , DOI: ( /bja/ael011) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions


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