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Volume 133, Issue 2, Pages (August 2007)

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Presentation on theme: "Volume 133, Issue 2, Pages (August 2007)"— Presentation transcript:

1 Volume 133, Issue 2, Pages 496-506 (August 2007)
Relationship Between Hepatic/Visceral Fat and Hepatic Insulin Resistance in Nondiabetic and Type 2 Diabetic Subjects  Amalia Gastaldelli, Kenneth Cusi, Maura Pettiti, Jean Hardies, Yoshinori Miyazaki, Rachele Berria, Emma Buzzigoli, Anna Maria Sironi, Eugenio Cersosimo, Ele Ferrannini, Ralph A. DeFronzo  Gastroenterology  Volume 133, Issue 2, Pages (August 2007) DOI: /j.gastro Copyright © 2007 AGA Institute Terms and Conditions

2 Figure 1 Relationship between age vs degree of obesity (BMI), liver fat content, VAT content, and SAT content in nondiabetic (●) and diabetic (○) subjects. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions

3 Figure 2 Relationship between BMI vs liver, visceral, and subcutaneous fat content in nondiabetic (●) and diabetic (○) subjects. The correlation between BMI and liver fat was found only in NGT subjects. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions

4 Figure 3 Relationship between liver fat and visceral and subcutaneous abdominal fat in nondiabetic (●) and diabetic (○) subjects. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions

5 Figure 4 Relationship between basal EGP and liver fat (%), VAT, SAT, and BMI in nondiabetic (●) and diabetic (○) subjects Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions

6 Figure 5 Relationship between basal gluconeogenic flux (GNG) vs liver fat (%) and VAT in nondiabetic (●) and diabetic (○) subjects. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions

7 Figure 6 Relationship between suppression of EGP during the insulin clamp vs liver fat (%) and VAT in nondiabetic (●) and diabetic (○) subjects. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions

8 Figure 7 Relationship between hepatic insulin clearance during the insulin clamp vs liver fat (%) in nondiabetic (●) and diabetic (○) subjects. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2007 AGA Institute Terms and Conditions


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