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A. Abdel Nazeer, S. Saito, S. Sayed, L. Hassan, F. Askar, W

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Presentation on theme: "A. Abdel Nazeer, S. Saito, S. Sayed, L. Hassan, F. Askar, W"— Presentation transcript:

1 Normal glucose enhances neuronal regeneration after lidocaine-induced injury 
A. Abdel Nazeer, S. Saito, S. Sayed, L. Hassan, F. Askar, W. Al-jahdari, T. Seki, O. Hideaki  British Journal of Anaesthesia  Volume 104, Issue 4, Pages (April 2010) DOI: /bja/aeq030 Copyright © 2010 The Author(s) Terms and Conditions

2 Fig 1 DRG cultured for 20 h, immediately before exposure to lidocaine (a–c), collapsed growth cones and shrinkage of neurites after exposure to lidocaine for 1 h in the three glucose conditions (d–f), Recovery of the collapsed cones 2 h after washing lidocaine out (g–i). Growth cones 24 h after wash (j–l). Neurite length 24 h after wash (m–o). British Journal of Anaesthesia  , DOI: ( /bja/aeq030) Copyright © 2010 The Author(s) Terms and Conditions

3 Fig 2 Growth cone collapse after 1 h exposure to lidocaine. *Significant difference compared with values in normal glucose (P<0.05). British Journal of Anaesthesia  , DOI: ( /bja/aeq030) Copyright © 2010 The Author(s) Terms and Conditions

4 Fig 3 LDH leakage after 1 h exposure to lidocaine at different glucose concentrations. *Significant difference compared with the values in normal glucose (P<0.05). +Significant difference compared with pre-exposure value (P<0.05). British Journal of Anaesthesia  , DOI: ( /bja/aeq030) Copyright © 2010 The Author(s) Terms and Conditions


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