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Beneficial value of testicular sperm extraction-AgarCyto in addition to the standard testicular biopsy for diagnosis of testicular germ cell tumors in.

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Presentation on theme: "Beneficial value of testicular sperm extraction-AgarCyto in addition to the standard testicular biopsy for diagnosis of testicular germ cell tumors in."— Presentation transcript:

1 Beneficial value of testicular sperm extraction-AgarCyto in addition to the standard testicular biopsy for diagnosis of testicular germ cell tumors in nonobstructive azoospermia  Marie-Louise Hessel, M.D., Liliana Ramos, Ph.D., Kathleen W.M. D'Hauwers, M.D., Ph.D., Didi D.M. Braat, M.D., Ph.D., Christina A. Hulsbergen-van de Kaa, M.D., Ph.D.  Fertility and Sterility  Volume 105, Issue 2, Pages e1 (February 2016) DOI: /j.fertnstert Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Evaluation of spermatogenesis and germ cell neoplasia in situ in the standard testicular biopsy and testicular sperm extraction (TESE)-AgarCyto. Case with spermatogenesis (A, B) and focal germ cell neoplasia in situ (C–H). In comparison to the standard biopsy (A, C, E, G) the TESE-AgarCyto (B, D, F, H) shows moderate (lower half of D) to severe (upper half of D) mechanical damage. However, immunohistochemical staining is intact (E and F: OCT3/4; G and H: PLAP; Original magnification for all panels, ×200). Fertility and Sterility  , e1DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

3 Supplemental Figure 1 Composition of the cohort. GCNIS = germ cell neoplasia in situ; NOA = nonobstructive azoospermia; TESE = testicular sperm extraction. Fertility and Sterility  , e1DOI: ( /j.fertnstert ) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions


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