1. Volume 85, Issue 5, Pages 1208-1213 (May 2014)
Milder clinical aspects of X-linked Alport syndrome in men positive for the collagen IV α5 chain 
Yuya Hashimura, Kandai Nozu, Hiroshi Kaito, Koichi Nakanishi, Xue Jun Fu, Hiromi Ohtsubo, Fusako Hashimoto, Masafumi Oka, Takeshi Ninchoji, Shingo Ishimori, Naoya Morisada, Natsuki Matsunoshita, Naohiro Kamiyoshi, Norishige Yoshikawa, Kazumoto Iijima 
Kidney International 
Volume 85, Issue 5, Pages (May 2014)
DOI: /ki
Copyright © 2014 International Society of Nephrology Terms and Conditions

2. Figure 1
Flow diagram showing patient recruitment and analysis. Fifty-two proven XLAS males were finally enrolled in this study. AS, Alport syndrome; XLAS, AS patients showing X-linked inheritance.
Kidney International  , DOI: ( /ki )
Copyright © 2014 International Society of Nephrology Terms and Conditions

3. Figure 2
Distribution map of COL4A5 missense mutations. Black circles define the positions of missense mutations in the negative group, and open circles show the positions of missense mutations in the positive group.
Kidney International  , DOI: ( /ki )
Copyright © 2014 International Society of Nephrology Terms and Conditions

4. Figure 3
Age at onset of end-stage renal disease (ESRD) in negative (n=14) and positive group (n=15) patients and their affected male family members. The onset age was significantly lower in negative group compared with positive group patients (24.00±14.2 and 37.53±16.30 years, respectively; P=0.018).
Kidney International  , DOI: ( /ki )
Copyright © 2014 International Society of Nephrology Terms and Conditions

5. Figure 4
Probability of hearing loss in the type IV collagen α5 (α5(IV))-positive and -negative groups. The median age for developing hearing loss was 13 years in the negative group, whereas no patients in the positive group developed hearing loss.
Kidney International  , DOI: ( /ki )
Copyright © 2014 International Society of Nephrology Terms and Conditions