1. Mortality rates and walking ability transition after lower limb major amputation in hemodialysis patients 
Fukashi Serizawa, MD, PhD, Shigeru Sasaki, MD, PhD, Shinobu Fujishima, RN, Daijirou Akamatsu, MD, PhD, Hitoshi Goto, MD, PhD, Noritoshi Amada, MD, PhD 
Journal of Vascular Surgery 
Volume 64, Issue 4, Pages (October 2016)
DOI: /j.jvs
Copyright © 2016 Society for Vascular Surgery Terms and Conditions

2. Fig 1
Overall survival and additional amputation-free survival (AAFS). A, Kaplan-Meier curve estimates the survival rate after first major amputation: 80 of 108 patients died by the end of June The median time to death was 19.9 months (95% confidence interval [CI],  months), and the leading cause of death was cardiac. Causes of death were calculated based on a partial population of 80 patients. B, AAFS was estimated from the Kaplan-Meier curve: 31 of 108 patients underwent additional amputation, and 28 of 31 amputations (90.3%) occurred ≤1 year. Median time for AAFS was 6.7 months (95% CI,  months). SE, Standard error.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2016 Society for Vascular Surgery Terms and Conditions

3. Fig 2
Survival according to age category and amputation level. A, Patients were grouped by younger (≤70 years; n = 60) and older (≥71 years; n = 48) age according to their age at the first amputation. Survival rates of younger vs older were 85.0% vs 81.2% at 30 days, 69.5% vs 40.7% at 1 year, and 25.3% vs 3.3% at 5 years. Mean survival times were 38.3 ± 4.9 months (95% confidence interval [CI],  months) in the younger group and 16.0 ± 2.8 months (95% CI,  months) in the older group; this difference was significant (P < .001). B, We excluded one patient who had bilateral amputation and included the remaining 107 patients in the analysis, 44 with above-knee (AK) amputation (AKA) and 63 with below-knee (BK) amputation (BKA). The survival rates of the AK vs BK groups were 77.3% vs 87.3% at 30 days, 48.3% vs 63.3% at 1 year, and 9.8% vs 18.2% at 5 years. Mean survival times were 21.2 ± 3.8 months (95% CI,  months) in the AK group and 33.4 ± 4.5 months (95% CI,  months) in the BK group; this difference was not significant (P = .06). SE, Standard error.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2016 Society for Vascular Surgery Terms and Conditions

4. Fig 3
Ambulant status and survival. A, We compared the walking ability of 103 patients (data were missing for five patients) before and after major amputation (left). Among the 103 patients, only nine (8.7%) retained their walking ability after major amputation, and 26 (25.2%) died ≤60 days. The exclusion of patients with short-term mortality reduced the rate of ambulant patients from 33.7% to 11.6%, changed that of wheelchair use from 45.0% to 48.0%, and increased the rate of bedridden patients from 20.7% to 40.2% (right). B, Patients were divided into two groups according to their ambulatory status at first amputation. Survival rates (ambulatory vs others) were 90.3% vs 93.1% at 30 days, 69.9% vs 49.8% 1 year, and 24.8% vs 13.0% at 5 years. Mean survival times were 40.5 ± 7.2 months (95% confidence interval [CI],  months) in the ambulatory group and 23.5 ± 3.5 months (95% CI,  months) in the other group; this difference was significant (P = .02). SE, Standard error.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2016 Society for Vascular Surgery Terms and Conditions