1. Generation, Study, and Application of Dicationic Intermediates
Douglas A. Klumpp, Department of Chemistry, Northern Illinois University, DeKalb, IL
During the past two years, we have exploited the high reactivities of dicationic, superelectrophilic intermediates in the development of new synthetic methodologies. Some of these conversions are shown below. Besides the new synthetic methodologies, the work has also provided key insights into the chemistry of these reactive, highly charged intermediates.
Superacid-promoted reactions of a-keto and b-ketoamides: J. Org. Chem , 73, ; 2007, 72,
Synthesis of polycyclic aromatic compounds: J. Org. Chem , 73,
Aza-Nazarov reaction: Org. Lett , 9,
Single electron transfer (SET) reactions with superelectrophiles: J. Am. Chem. Soc., manuscript in revision