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Welcome to Who Wants to be a Genetic

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1 Welcome to Who Wants to be a Genetic
50:50 15 $1 Million 14 $500,000 Welcome to Who Wants to be a Genetic Millionaire? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

2 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

3 He’s the Father of modern genetics
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 He’s the Father of modern genetics $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Neils Bohr B: Charles Darwin C: Gregor Mendel D: Ashley Darwin

4 He’s the Father of modern genetics
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 He’s the Father of modern genetics $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Neils Bohr B: Charles Darwin C: Gregor Mendel D: Ashley Darwin

5 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

6 Darwin lived in this European country
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 Darwin lived in this European country 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Scotland B: Austria C: Denmark D: Germany

7 Darwin lived in this European country
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 Darwin lived in this European country 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Scotland B: Austria C: Denmark D: Germany

8 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

9 The letter combination that represents a trait
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 The letter combination that represents a trait 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Genotype B: Phenotype C: Pedigree D: Stereotype

10 The letter combination that represents a trait
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 The letter combination that represents a trait 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Genotype B: Phenotype C: Pedigree D: Stereotype

11 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

12 The phase of mitosis where centrioles first appear
15 $1 Million 14 $500,000 13 $250,000 12 The phase of mitosis where centrioles first appear $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Telophase B: Metaphase C: Anaphase D: Prophase

13 The phase of mitosis where centrioles first appear
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 The phase of mitosis where centrioles first appear 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Telophase B: Metaphase C: Anaphase D: Prophase

14 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

15 The fraction of round, green peas in Mendel’s F2 generation
15 $1 Million 14 $500,000 The fraction of round, green peas in Mendel’s F2 generation 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: 9/16 B: 1/4 C: 1/16 D: 3/16

16 The fraction of round, green peas in Mendel’s F2 generation
15 $1 Million 14 $500,000 The fraction of round, green peas in Mendel’s F2 generation 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: 9/16 B: 1/4 C: 1/16 D: 3/16

17 You’ve Reached the $1,000 Milestone! Congratulations! Congratulations!

18 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

19 15 $1 Million 14 $500,000 13 $250,000 The probable blood type of the child of a heterozygous Type A father and Type AB mother 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Type AB B: Type A C: Type O D: Type B

20 15 $1 Million 14 $500,000 The most likely blood type of the child of a heterozygous Type A father and Type AB mother 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Type AB B: Type A C: Type O D: Type B

21 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

22 Which of the following is not a single gene defect?
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 Which of the following is not a single gene defect? 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Sickle cell anemia B: Huntington’s disease C: Down’s Syndrome D: Muscular dystrophy

23 Which of the following is not a single gene defect?
15 $1 Million 14 $500,000 Which of the following is not a single gene defect? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Sickle cell anemia B: Huntington’s disease C: Down Syndrome D: Muscular dystrophy

24 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

25 Which is not required for DNA testing?
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 Which is not required for DNA testing? 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Gel paper B: Power source C: Agarose gel D: Restriction enzymes

26 Which is not required for DNA testing?
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 Which is not required for DNA testing? 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Gel paper B: Power source C: Agarose gel D: Restriction enzymes

27 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

28 Errors in meiosis usually occur during which phase?
15 $1 Million 14 $500,000 Errors in meiosis usually occur during which phase? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Anaphase II B: Prophase I C: Anaphase I D: Prophase II

29 Errors in meiosis usually occur during which phase?
15 $1 Million 14 $500,000 Errors in meiosis usually occur during which phase? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Anaphase II B: Prophase I C: Anaphase I D: Prophase II

30 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

31 A person with an improperly constructed larynx likely has this:
15 $1 Million 14 $500,000 A person with an improperly constructed larynx likely has this: 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Huntington’s disease B: Cri-du-chat syndrome C: Turner syndrome D: Achondroplasia

32 A person with an improperly constructed larynx likely has this:
15 $1 Million 14 $500,000 A person with an improperly constructed larynx likely has this: 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Huntington’s disease B: Cri-du-chat syndrome C: Turner syndrome D: Achondroplasia

33 You’ve Reached the $32,000 Milestone! Congratulations!

34 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

35 15 $1 Million 14 $500,000 If a heterozygous couple has a normal child but has two grandchildren: a normal granddaughter and a grandson with a recessive disorder, it is likely due to what kind of inheritance? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: X-linked B: Co-dominant C: Autosomal dominant D: Autosomal recessive

36 15 $1 Million If a heterozygous couple has a normal child but has two grandchildren: a normal granddaughter and a grandson with a recessive disorder, it is likely due to what kind of inheritance? 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: X-linked B: Co-dominant C: Autosomal dominant D: Autosomal recessive

37 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

38 Which organism has the greatest number of chromosomes?
15 $1 Million 14 $500,000 Which organism has the greatest number of chromosomes? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Fruit fly B: Mouse C: Yeast D: Human

39 Which organism has the greatest number of chromosomes?
15 $1 Million 14 $500,000 Which organism has the greatest number of chromosomes? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Fruit fly B: Mouse C: Yeast D: Human

40 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

41 A karyotype would not adequately show…
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 A karyotype would not adequately show… 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Trisomy 21 B: Fragile ‘X’ syndrome C: Klinefelter syndrome D: Tay-Sachs disease

42 A karyotype would not adequately show…
15 $1 Million 14 $500,000 13 $250,000 12 $125,000 A karyotype would not adequately show… 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: Trisomy 21 B: Fragile ‘X’ syndrome C: Klinefelter syndrome D: Tay-Sachs disease

43 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

44 15 $1 Million 14 $500,000 For autosomal dominant inheritance, which is not possible of the F2 generation of Dd and DD parents? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: 50% Dd; 50% dd B: 50% DD; 50% Dd D: 25% DD; 25% dd C: 100% DD

45 15 $1 Million 14 $500,000 For autosomal dominant inheritance, which is not possible of the F2 generation of Dd and DD parents? 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: 50% Dd; 50% dd B: 50% DD; 50% Dd D: 25% DD; 25% dd C: 100% DD

46 15 $1 Million 14 $500,000 13 $250,000 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 1 $100

47 Study the following pedigree…

48 This pedigree demonstrates the following inheritance pattern:
15 $1 Million 14 $500,000 13 $250,000 This pedigree demonstrates the following inheritance pattern: 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: X-linked recessive B: X-linked dominant C: Autosomal dominant D: Autosomal recessive

49 This pedigree demonstrates the following inheritance pattern:
15 $1 Million 14 $500,000 13 $250,000 This pedigree demonstrates the following inheritance pattern: 12 $125,000 11 $64,000 10 $32,000 9 $16,000 8 $8,000 7 $4,000 6 $2,000 5 $1,000 4 $500 3 $300 2 $200 50:50 1 $100 A: X-linked recessive B: X-linked dominant C: Autosomal dominant D: Autosomal recessive

50 YOU WIN $1 MILLION DOLLARS!


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