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Primary Thymic Mucosa-Associated Lymphoid Tissue Lymphoma: Diagnostic Tips  Kimihiro Shimizu, MD, PhD, Junji Yoshida, MD, PhD, Seiichi Kakegawa, MD, Jun.

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Presentation on theme: "Primary Thymic Mucosa-Associated Lymphoid Tissue Lymphoma: Diagnostic Tips  Kimihiro Shimizu, MD, PhD, Junji Yoshida, MD, PhD, Seiichi Kakegawa, MD, Jun."— Presentation transcript:

1 Primary Thymic Mucosa-Associated Lymphoid Tissue Lymphoma: Diagnostic Tips 
Kimihiro Shimizu, MD, PhD, Junji Yoshida, MD, PhD, Seiichi Kakegawa, MD, Jun Astumi, MD, Kyoichi Kaira, MD, PhD, Kiyohiro Oshima, MD, PhD, Tomomi Miyanaga, MD, PhD, Mitsuhiro Kamiyoshihara, MD, PhD, Kanji Nagai, MD, PhD, Izumi Takeyoshi, MD, PhD  Journal of Thoracic Oncology  Volume 5, Issue 1, Pages (January 2010) DOI: /JTO.0b013e3181c07df8 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Magnetic resonance imaging (MRI) and gross appearance of mucosa-associated lymphoid tissue (MALT) thymic lymphoma. Case 4:, upper image, transverse T2-weighted MRI showed a multilocular cyst in the right anterior mediastinum. Lower image: the cut surface of the tumor shows multiple follicular cysts. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181c07df8) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Histologic appearance of thymic mucosa-associated lymphoid tissue (MALT) lymphoma. A, Reactive lymph follicles with germinal center and cystic formations in the tumor. B, Lymphoepithelial lesion formed by a Hassall's corpuscle infiltrated by centrocyte-like (CCL) cells. C, The epithelium lining the cyst is invaded by CCL cells forming the lymphoepithelial lesion. The cyst contains eosinophilic material. D, Mature plasma cells are found around the vessels. HE, hematoxylin and eosin. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181c07df8) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Diagnostic flow chart for thymic mucosa-associated lymphoid tissue (MALT) lymphoma. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181c07df8) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

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