1. Vancouver Risk Calculator Compared with ACR Lung-RADS in Predicting Malignancy: Analysis of the National Lung Screening Trial  
When using CT to screen for lung cancer, the Vancouver risk calculator (VRC) is superior to ACR Lung-RADS in predicting malignancy.
On an overall per-nodule basis, the sensitivity, specificity, and accuracy for VRC and Lung-RADS were 93%, 90%, and 90% for VRC and 87%, 83%, and 83% for Lung-RADS, respectively (P = .077, P<.001, and P < .001, respectively).
Future revisions of Lung-RADS may benefit from incorporation of some parameters in the VRC to improved sensitivity in identifying individuals with malignant nodules.
63-year-old with a 7-mm solid nodule (arrow). LungRADS category was 3 (false negative); VRC probability was 11% (true positive). The right upper lobe location and the presence of emphysema (not considered in the Lung-RADS score) increased the VRC score to above the malignant threshold of 5%.
White CS et al. Published Online: Jan 22,
White CS et al. Published Online: Jan 22, 2019