1. Volume 114, Issue 2, Pages 295-304 (February 1998)
Genetic analysis of long-term Barrett's esophagus epithelial cultures exhibiting cytogenetic and ploidy abnormalities 
M.Corinna Palanca-Wessels, Michael T. Barrett, Patricia C. Galipeau, Katherine L. Rohrer, Brian J. Reid, Peter S. Rabinovitch 
Gastroenterology 
Volume 114, Issue 2, Pages (February 1998)
DOI: /S (98)
Copyright © 1998 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Phase-contrast microscopy of Barrett's epithelial cell cultures. The monolayer cultures show a cobblestone-like morphology at confluency that is typical of epithelial cells. (A) A primary culture showing cells explanting from pieces of tissue after 7 days in culture; this particular culture was eventually overgrown by fibroblasts subsequent to the first passage. (B) A representative long-term Barrett's epithelial culture, CP-94251, at passage 8.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

3. Fig. 1
Phase-contrast microscopy of Barrett's epithelial cell cultures. The monolayer cultures show a cobblestone-like morphology at confluency that is typical of epithelial cells. (A) A primary culture showing cells explanting from pieces of tissue after 7 days in culture; this particular culture was eventually overgrown by fibroblasts subsequent to the first passage. (B) A representative long-term Barrett's epithelial culture, CP-94251, at passage 8.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

4. Fig. 2
Flow-cytometric analyses of asynchronous and 4N sorted Barrett's epithelial cultures. Cell cycle distribution of asynchronous cells is shown in A–D. Note the elevated fraction of cells with G2/tetraploid (4N) DNA content. (A) CP-52731, (B) CP-18821, (C) CP-94251, and (D) KR DNA histograms of 4N sorted cells from one of the Barrett's epithelial cultures, CP-18821, are shown in E and F. Cells (4N sorted) from CP were returned to culture and harvested 72 hours later. Sorted 4N cells: E, immediately after sort; and F, 72 hours later.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

5. Fig. 3
Karyotypes of a (A) near-diploid cell and (B) near-tetraploid cell from culture CP Clonal abnormalities found in the near-diploid cell that are also seen in the near-tetraploid cell include a translocation onto the 9p chromosome, a 17p abnormality, and an unidentified marker chromosome.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

6. Fig. 3
Karyotypes of a (A) near-diploid cell and (B) near-tetraploid cell from culture CP Clonal abnormalities found in the near-diploid cell that are also seen in the near-tetraploid cell include a translocation onto the 9p chromosome, a 17p abnormality, and an unidentified marker chromosome.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions