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Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Lung Cancer: A Systematic Review with Meta-Analysis  Ping Zhan, MD,

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Presentation on theme: "Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Lung Cancer: A Systematic Review with Meta-Analysis  Ping Zhan, MD,"— Presentation transcript:

1 Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Lung Cancer: A Systematic Review with Meta-Analysis  Ping Zhan, MD, Jing Wang, MD, Xiao-jing Lv, MD, Qin Wang, MD, Li-xin Qiu, MD, Xin-qing Lin, MD, Li-ke Yu, MD, Yong Song, MD, PhD  Journal of Thoracic Oncology  Volume 4, Issue 9, Pages (September 2009) DOI: /JTO.0b013e3181a97e31 Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 The flow diagram of search strategy.
Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a97e31) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Meta-analysis (Forest plot) of the 44 evaluable studies assessing vascular endothelial growth factor (VEGF) in non-small cell lung cancer (NSCLC) (A); the five evaluable studies assessing VEGF in adenocarcinoma (B); the five evaluable studies assessing VEGF in small cell lung cancer (SCLC) (C); the seven evaluable studies assessing VEGF in stage I NSCLC (D); the eight evaluable studies assessing VEGFC in NSCLC (E); the four evaluable studies assessing vascular endothelial growth factor receptor 3/Flt-1 in NSCLC (F). Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a97e31) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 2 Meta-analysis (Forest plot) of the 44 evaluable studies assessing vascular endothelial growth factor (VEGF) in non-small cell lung cancer (NSCLC) (A); the five evaluable studies assessing VEGF in adenocarcinoma (B); the five evaluable studies assessing VEGF in small cell lung cancer (SCLC) (C); the seven evaluable studies assessing VEGF in stage I NSCLC (D); the eight evaluable studies assessing VEGFC in NSCLC (E); the four evaluable studies assessing vascular endothelial growth factor receptor 3/Flt-1 in NSCLC (F). Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a97e31) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 3 Contour-enhanced funnel plot of the 44 evaluable studies assessing vascular endothelial growth factor (VEGF) in non-small cell lung cancer (NSCLC). Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a97e31) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions


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