1. Chapter 51 Management of Patients With Immunodeficiency

2. Immunodeficiency Disorders
Primary
Genetic
May affect phagocytic function, B cells and/or T cells, or the complement system
Secondary
Acquired
HIV/AIDS
Related to underlying disorders, diseases, toxic substances, or medications

3. Primary Immunodeficiencies
Usually seen in infants and young children
Manifestations: vary according to type; severe or recurrent infections; failure to thrive or poor growth; and positive family history
Potential complications: recurrent, severe, potentially fatal infections; related blood dyscrasias and malignancies
Treatment: varies by type; treatment of infection; pooled plasma or immunoglobulin; GM-CSF or GCSF; thymus graft, stem cell, or bone marrow transplant
See Table 51-1

4. Nursing Management Monitor for signs and symtoms of infections
Symptoms of inflammatory response may be blunted
Monitor lab values
Promote good nutrition
Address anxiety, stress, and coping
Strategies to reduce risk of infection
Handwashing and strict aseptic technique
Patient protection and hygiene measures: skin care, promote normal bowel and bladder function, and pulmonary hygiene

5. Patient Teaching Signs and symptoms of infection Medication teaching
Prevention of infection
Handwashing
Avoid crowds and persons with infections
Hygiene and cleaning
Nutrition and diet
Lifestyle modifications to reduce risk
Follow-up care